Evidence map›Paper›PMID 27994864›Full record

ArticleClinical kidney journal2016

Diabetic kidney disease patients on hemodialysis: a retrospective survival analysis across different socioeconomic groups.

Madhusudan Vijayan, Saranya Radhakrishnan, Georgi Abraham, Milly Mathew, Krishnaswamy Sampathkumar, Nevin Philip Mancha

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Article in Clinical kidney journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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3 · Its place in the literature

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5 citing papers in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Madhusudan VijayanKilpauk Medical College, Chennai, India.
Saranya RadhakrishnanMacaulay Honors College, New York, NY, USA.
Georgi AbrahamPondicherry Institute of Medical Science, Pondicherry, India; Madras Medical Mission Hospital, Chennai, India; Tamil Nadu Kidney Research (TANKER) Foundation, Chennai, India.
Milly MathewPondicherry Institute of Medical Science, Pondicherry, India.
Krishnaswamy SampathkumarMeenakshi Mission Hospital and Research Center, Madurai, India.
Nevin Philip ManchaPondicherry Institute of Medical Science, Pondicherry, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic kidney disease is the leading cause of stage 5 chronic kidney disease (CKD) in India. Renal replacement therapy (RRT) is accessible to very few patients because of socioeconomic deprivation. We studied the effect of diabetes and socioeconomic status on the outcome of patients on maintenance hemodialysis (MHD).

methodsWe retrospectively analyzed the outcome of 897 patients (629 males/268 females; mean age ± standard deviation 48.69 ± 14.27 years) initiated on MHD from 2003 to 2009 at five dialysis centers in south India. There were 335 type 2 diabetic patients and 562 non-diabetic patients. Group 1 comprised the self-paying patients (518 patients) and Group 2 included the TANKER Foundation charity dialysis patients (379 patients). We compared the 5-year survival rates of Group 1 versus Group 2 and also those of diabetic versus non-diabetic patients, using the Kaplan-Meier survival estimator.

resultsOf the 897 patients, 166 patients survived, 350 died, 234 were lost to follow-up, 137 had renal transplantation and 10 patients were transferred to peritoneal dialysis. The 5-year survival rates after censoring were 20.7 and 38.2% for diabetic and non-diabetic patients, respectively (P < 0.001). The survival rate of diabetic patients was significantly lower, compared with non-diabetic patients, in Group 2 (P < 0.001), but not significantly lower in Group 1 (P = 0.226).

conclusionsDiabetic patients have poor survival rates on MHD, especially those from poor socioeconomic groups. Due to scarce RRT facilities and poor survival rates of diabetic patients, prevention, early detection and management of diabetic CKD patients should be the way to go forward.

Indexed as

diabetic kidney diseasehemodialysissocioeconomic classsurvival analysis

Identifiers

PMID27994864
PMCPMC5162407

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