ArticleInternational journal of preventive medicine2016
Effects of Pomegranate Seed Oil on Metabolic State of Patients with Type 2 Diabetes Mellitus.
Article in International journal of preventive medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- The effect of pomegranate products on glycemic profile in adults: a GRADE- assessed systematic review and dose-response meta-analysis of randomized controlled trials.BMC nutrition · 2025Pooled it
- Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2022Pooled it
- Lack of efficacy of pomegranate supplementation for glucose management, insulin levels and sensitivity: evidence from a systematic review and meta-analysis.Nutrition journal · 2017Pooled it
- Acute Effects of a High-Fat Meal Enriched with Pomegranate Seed Oil on Postprandial Lipemia and Endothelial Function in Postmenopausal Women: a Randomized Controlled Crossover Trial.The Journal of nutrition · 2026Trial
- Punicic Acid: A Potential Nutraceutical Compound in Pomegranate Seed Oil and Its Cardiovascular Benefits.Foods (Basel, Switzerland) · 2025Article
- Punicic acid alleviates methylglyoxal-induced oocyte dysfunction during in vitro maturation in mouse species.PloS one · 2025Article
- The effects of pomegranate consumption on obesity indices in adults: A systematic review and meta-analysis.Food science & nutrition · 2024Review
- Therapeutic Effects ofJournal of nutrition and metabolism · 2021Review
- Effects of green coffee extract on fasting blood glucose, insulin concentration and homeostatic model assessment of insulin resistance (HOMA-IR): a systematic review and meta-analysis of interventional studies.Diabetology & metabolic syndrome · 2019Review
- Association between unfavorable lipid profile and glycemic control in patients with type 2 diabetes mellitus.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2017Article
- Clinical sensitivity and specificity of serum total bilirubin - A study on thyroid status in clinically euthyroid non-obese, overweight, and obese type 2 diabetics.International journal of health sciencesArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRapid increasing prevalence of diabetes mellitus is a serious health concern in the world. New data determined that the pathogenesis of diabetes mellitus is chronic low-grade inflammation, resulting insulin resistance. Pomegranate seed oil (PSO) has anti-inflammatory effects; though it may reduce insulin resistance and improve glycemia in diabetes mellitus. The present study has been designed to investigate the effects of PSO as a natural dietary component on metabolic state of patients with Type 2 diabetes mellitus.
methodsIn a randomized double-blind clinical trial study, 80 patients (28 men) with Type 2 diabetes were randomly allocated to the intervention and control groups. The intervention group consumed PSO capsules, containing 1000 mg PSO twice daily (2000 mg PSO), whereas controls take placebo for 8 weeks. The participants followed their previous dietary patterns and medication use. Dietary factors and metabolic factors including lipid profile, fasting plasma sugar, and insulin and were assayed at the baseline and after 8 weeks.
resultsParticipants in two intervention and control group were similar regarding anthropometric and the dietary factors at baseline and after trial (
conclusionsConsumption of 2000mg PSO per day for 8 weeks had no effect on FBS, insulin resistance and lipid profile in diabetic patients.
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Registered trials
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