Evidence map›Paper›PMID 27994790›Full record

ArticleAsian spine journal2016

A Nationwide Retrospective Study of Opioid Management Patterns in 2,468 Patients with Spinal Pain in Korea.

Sung-Soo Chung, Chun-Kun Park, Kyu-Jung Cho, Kyoung Hyo Choi, Jin-Hyok Kim, Sung-Bum Kim, Sung-Uk Kuh, Jae Chul Lee, Jae Hyup Lee, Kyu-Yeol Lee and 7 more

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Asian spine journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03161795 (Addressing the Risks of Long-Term Opioid Therapy in Chronic Noncancer Pain), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03161795 completednot on this mapstarted 2017, after this paper: background citation

Addressing the Risks of Long-Term Opioid Therapy in Chronic Noncancer Pain: A National, Multicenter, and Observational Cross-sectional Study in South Korea

Typeobservational_patient_registrySponsorSeoul National UniversityRan2017 to 2018Enrolled258ConditionsChronic Noncancer Pain, Opioid-Related Disorders
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 1 country.

Sung-Soo ChungDepartment of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Chun-Kun ParkDepartment of Neurosurgery, Good Doctor Teun Teun Hospital, Anyang, Korea.
Kyu-Jung ChoDepartment of Orthopedic Surgery, Inha University Hospital, Inha University School of Medicine, Incheon, Korea.
Kyoung Hyo ChoiDepartment of Rehabilitation Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jin-Hyok KimDepartment of Orthopedic Surgery, Inje University Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
Sung-Bum KimDepartment of Neurosurgery, Kyung Hee University Medical Center, Kyung Hee University School of Medicine, Seoul, Korea.
Sung-Uk KuhDepartment of Neurosurgery, Gangnam Severance Hospital, Yonsei University Medical Center, Seoul, Korea.
Jae Chul LeeDepartment of Orthopedic Surgery, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea.
Jae Hyup LeeDepartment of Orthopedic Surgery, SMG-SNU Boramae Medical Center, Seoul, Korea.
Kyu-Yeol LeeDepartment of Orthopedic Surgery, Dong-A University Medical Center, Dong-A University College of Medicine, Busan, Korea.
Sun-Ho LeeDepartment of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Seong-Hwan MoonDepartment of Orthopedic Surgery, Severance Hospital, Yonsei University Health System, Seoul, Korea.
Si-Young ParkDepartment of Orthopedic Surgery, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.
Jae Hang ShimDepartment of Anesthesia and Pain Medicine, Hanyang University Guri Hospital, Hanyang University College of Medicine, Guri, Korea.
Byung-Chul SonDepartment of Neurosurgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Myung Ha YoonDepartment of Anesthesiology and Pain Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea.
Hye-Jeong ParkMundipharma Korea Ltd., Seoul, Korea.
SNUH SMG-SNU Boramae Medical Center · KRCatholic University of Korea · KRChonnam National University Hospital · KRInha University Hospital · KRInje University Sanggye Paik Hospital · KRKorea University · KRSamsung Medical Center · KRSungkyunkwan University · KRUlsan College · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective patient data collection and investigator survey. PURPOSE: To investigate patterns of opioid treatment for pain caused by spinal disorders in Korea. OVERVIEW OF LITERATURE: Opioid analgesic prescription and adequacy of consumption measures in Korea have markedly increased in the past decade, suggesting changing patterns in pain management practice; however, there is lack of integrated data specific to Korean population.

methodsPatient data were collected from medical records at 34 university hospitals in Korea. Outpatients receiving opioids for pain caused by spinal disorders were included in the study. Treatment patterns, including opioid types, doses, treatment duration, outcomes, and adverse drug reactions (ADRs), were evaluated. Investigators were interviewed on their perceptions of opioid use for spinal disorders.

resultsAmong 2,468 analyzed cases, spinal stenosis (42.8%) was the most common presentation, followed by disc herniation (24.2%) and vertebral fracture (17.5%). In addition, a greater proportion of patients experienced severe pain (73.9%) rather than moderate (19.9%) or mild (0.7%) pain. Oxycodone (51.9%) and fentanyl (50.8%) were the most frequently prescribed opioids; most patients were prescribed relatively low doses. The median duration of opioid treatment was 84 days. Pain relief was superior in patients with longer treatment duration (≥2 months) or with nociceptive pain than in those with shorter treatment duration or with neuropathic or mixed-type pain. ADRs were observed in 8.6% of cases. According to the investigators' survey, "excellent analgesic effect" was a perceived advantage of opioids, while safety concerns were a disadvantage.

conclusionsOpioid usage patterns in patients with spinal disorders are in alignment with international guidelines for spinal pain management. Future prospective studies may address the suitability of opioids for spinal pain treatment by using appropriate objective measurement tools.

Indexed as

Chronic painOpioidSpinal diseasesSpine

Identifiers

PMID27994790
PMCPMC5165004
OpenAlexW2562496580

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.