Evidence map›Paper›PMID 27994764›Full record

ArticleACS medicinal chemistry letters2016

Synthesis and Bioevaluation of 3,6-Diaryl-[1,2,4]triazolo[4,3-

Qile Xu, Yueting Wang, Jingwen Xu, Maolin Sun, Haiqiu Tian, Daiying Zuo, Qi Guan, Kai Bao, Yingliang Wu, Weige Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Exploration of Novel Scaffolds Targeting CytochromeInternational journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qile XuKey Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
Yueting WangKey Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
Jingwen XuDepartment of Pharmacology, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
Maolin SunKey Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
Haiqiu TianKey Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
Daiying ZuoDepartment of Pharmacology, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
Qi GuanKey Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
Kai BaoKey Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenhe District, Shenyang 110016, China; Gordon Center for Medical Imaging, Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02214, United States.
Yingliang WuDepartment of Pharmacology, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.
Weige ZhangKey Laboratory of Structure-Based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University , 103 Wenhua Road, Shenhe District, Shenyang 110016, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 3,6-diaryl-[1,2,4]triazolo[4,3-

Indexed as

[1,2,4]Triazolo[4,3-b]pyridazinecolchicine binding sitecombretastatin A-4molecular modelingtubulin

Identifiers

PMID27994764
PMCPMC5150690

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.