Evidence map›Paper›PMID 27994754›Full record

ArticleACS medicinal chemistry letters2016

Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer's Disease.

Elena Simoni, Roberta Caporaso, Christian Bergamini, Jessica Fiori, Romana Fato, Przemyslaw Miszta, Sławomir Filipek, Filippo Caraci, Maria Laura Giuffrida, Vincenza Andrisano and 3 more

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Polyamine-Drug Conjugates: Do They Boost Drug Activity?Molecules (Basel, Switzerland) · 2023
    Review
  2. Review
  3. Article
  4. Profiling donepezil template into multipotent hybrids with antioxidant properties.Journal of enzyme inhibition and medicinal chemistry · 2018
    Review
  5. Review
  6. The roles of polyamines in microorganisms.World journal of microbiology & biotechnology · 2017
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Elena SimoniDepartment of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
Roberta CaporasoDepartment of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
Christian BergaminiDepartment of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
Jessica FioriDepartment of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
Romana FatoDepartment of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
Przemyslaw MisztaFaculty of Chemistry, Biological & Chemical Research Centre University of Warsaw , Pasteura 1, 02093 Warsaw, Poland.
Sławomir FilipekFaculty of Chemistry, Biological & Chemical Research Centre University of Warsaw , Pasteura 1, 02093 Warsaw, Poland.
Filippo CaraciIRCCS Associazione Oasi Maria S.S., Institute for Research on Mental Retardation and Brain Aging, Via Conte Ruggero 73, 94018 Troina, Enna, Italy; Department of Drug Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy.
Maria Laura GiuffridaInstitute of Biostructure and Bioimaging, National Research Council (CNR) , Via P. Gaifami 18, 95126 Catania, Italy.
Vincenza AndrisanoDepartment for Life Quality Studies, Alma Mater Studiorum-University of Bologna , Corso D'Augusto 237, 47921 Rimini, Italy.
Anna MinariniDepartment of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
Manuela BartoliniDepartment of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.
Michela RosiniDepartment of Pharmacy & Biotechnology, Alma Mater Studiorum-University of Bologna , Via Belmeloro 6, 40126 Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spermine conjugates

Indexed as

Alzheimer’s diseaseamyloidmitochondriapolyamines

Identifiers

PMID27994754
PMCPMC5150688

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.