Evidence map›Paper›PMID 27994739›Full record

ArticleACS medicinal chemistry letters2016

New Series of BPL Inhibitors To Probe the Ribose-Binding Pocket of

Jiage Feng, Ashleigh S Paparella, William Tieu, David Heim, Sarah Clark, Andrew Hayes, Grant W Booker, Steven W Polyak, Andrew D Abell

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. New Potent Sulfonamide-Based Inhibitors ofACS medicinal chemistry letters · 2024
    Article
  2. Article
  3. Structural Study of Potent Triazole-Based Inhibitors ofACS medicinal chemistry letters · 2023
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Jiage FengDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
Ashleigh S PaparellaDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
William TieuDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
David HeimDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
Sarah ClarkDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
Andrew HayesDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
Grant W BookerDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
Steven W PolyakDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
Andrew D AbellDepartment of Chemistry, Department of Molecular and Cellular Biology, and Centre for Nanoscale BioPhotonics (CNBP), University of Adelaide , Adelaide, South Australia 5005, Australia.
University of Adelaide · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Replacing the labile adenosinyl-substituted phosphoanhydride of biotinyl-5'-AMP with a N1-benzyl substituted 1,2,3-triazole gave a new truncated series of inhibitors of

Indexed as

antibioticsbiotin protein ligaseEnzyme inhibitorsStaphylococcus aureus

Identifiers

PMID27994739
PMCPMC5150696
OpenAlexW2530268391

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.