Evidence map›Paper›PMID 27994645›Full record

ArticleEcancermedicalscience2016

Next generation metronomic chemotherapy-report from the Fifth Biennial International Metronomic and Anti-angiogenic Therapy Meeting, 6-8 May 2016, Mumbai.

Pan Pantziarka, Lisa Hutchinson, Nicolas André, Sébastien Benzekry, Francesco Bertolini, Atanu Bhattacharjee, Shubhada Chiplunkar, Dan G Duda, Vikram Gota, Sudeep Gupta and 14 more

Open access · goldAbstract read
In one paragraph

Article in Ecancermedicalscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Metronomic Chemotherapy: A Novel Approach in Cancer Treatment.Asian Pacific journal of cancer prevention : APJCP · 2025
    Review
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 17 institutions in 9 countries.

Pan PantziarkaAnticancer Fund, Brussels, 1853 Strombeek-Bever, Belgium; The George Pantziarka TP53 Trust, London, UK.
Lisa HutchinsonNature Reviews Clinical Oncology, London N1 9XW, UK.
Nicolas AndréService d'hématologie et Oncologie Pédiatrique, Centre Hospitalo-Universitaire Timone Enfants, AP-HM, Aix-Marseille Université, INSERM, CRO2 UMR_S 911, Marseille, France; Metronomics Global Health Initiative, Marseille, France.
Sébastien BenzekryInria team MONC and Institut de Mathématiques de Bordeaux, Talence, France.
Francesco BertoliniEuropean Institute of Oncology, via Ripamonti 435, 20141 Milan, Italy.
Atanu BhattacharjeeMalabar Cancer Centre, Thalassery, India.
Shubhada ChiplunkarACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.
Dan G DudaDepartment of Radiation Oncology, Massachusetts General Hospital, Boston, MA, USA.
Vikram GotaACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.
Sudeep GuptaACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.
Amit JoshiTata Memorial Hospital, Mumbai, India.
Sadhana KannanACTREC, Tata Memorial Centre, Kharghar, Navi Mumbai 410210, India.
Robert KerbelBiological Sciences Platform, Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
Mark KieranDana-Farber Cancer Institute, Boston, MA, USA.
Antonella PalazzoDivision of Medical Senology, European Institute of Oncology, Via Ripamonti 435, 20141, Milan, Italy.
Aparna ParikhPRA Health Sciences, Mumbai, India.
Eddy PasquierINSERM UMR 911, Centre de Recherche en Oncologie Biologique et Oncopharmacologie, Aix-Marseille University, Marseille, France; Metronomics Global Health Initiative, Marseille, France.
Vijay PatilTata Memorial Hospital, Mumbai, India.
Kumar PrabhashTata Memorial Hospital, Mumbai, India.
Yuval ShakedDepartment of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Giselle Saulnier ShollerHelen DeVos Children's Hospital, Grand Rapids, Michigan, USA.
Jaroslav SterbaDepartment of Pediatric Oncology, University Hospital Brno and Faculty of Medicine, Masaryk University, Cernopolni 9, 613 00 Brno, Czech Republic; International Clinical Research Center, St. Anne's University Hospital and RECAMO, Masaryk Memorial Cancer Institute, Brno, Czech Republic.
David J WaxmanDepartment of Biology, Boston University, Boston, MA 02215, USA.
Shripad BanavaliTata Memorial Hospital, Mumbai, India; Metronomics Global Health Initiative, Marseille, France.
Tata Memorial Hospital · INCentre de Recherche en Cancérologie de Marseille · FRAdvanced Centre for Treatment, Research and Education in Cancer · INAnticancer Fund · BEBoston University · USDana-Farber Cancer Institute · USEuropean Institute of Oncology · ITHelen DeVos Children's Hospital · USInstitut de Mathématiques de Bordeaux · FRKleijnen Systematic Reviews (United Kingdom) · GBMalabar Cancer Centre · INMasaryk University · CZMassachusetts General Hospital · USPRA Health Sciences · INRipamonti · ITSunnybrook Research InstituteTechnion – Israel Institute of Technology · IL

Funding

HEPATIC METABOLISM OF ANTICANCER DRUGSR01CA049248 · NCI · DANA-FARBER CANCER INSTITUTE · PI WAXMAN, DAVID J · 1991 to 2014
$4.3M
NCI NIH HHS R01 CA049248
6 · The paper itself

Abstract

The 5

Indexed as

anti-angiogenicscancerdrug repurposingLMICMetronomic chemotherapy

Identifiers

PMID27994645
PMCPMC5130328
OpenAlexW2547204890

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.