Evidence map›Paper›PMID 27994601›Full record

ArticleCardiorenal medicine2016

The Renal Arterial Resistance Index Predicts Worsening Renal Function in Chronic Heart Failure Patients.

Massimo Iacoviello, Francesco Monitillo, Marta Leone, Gaetano Citarelli, Annalisa Doronzo, Valeria Antoncecchi, Agata Puzzovivo, Caterina Rizzo, Maria Silvia Lattarulo, Francesco Massari and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Cardiorenal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Renal resistive index for risk stratification and functional evaluation after transcatheter mitral valve repair: the ReRISE study.Clinical research in cardiology : official journal of the German Cardiac Society · 2026
    Article
  2. Assessing volume status in heart failure: The role of renal duplex ultrasound in evaluating cardiorenal morbidity and heart failure mortality.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Article
  3. Review
  4. Article
  5. The Incremental Role of Multiorgan Point-of-Care Ultrasounds in the Emergency Setting.International journal of environmental research and public health · 2023
    Review
  6. Article
  7. Review
  8. Article
  9. Effects of Smoking on Diabetic Nephropathy.Frontiers in clinical diabetes and healthcare · 2022
    Review
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Massimo IacovielloCardiology Unit, Cardiothoracic Department, Policlinic University Hospital, Bari, Italy.
Francesco MonitilloSchool of Cardiology, University of Bari, Bari, Italy.
Marta LeoneSchool of Cardiology, University of Bari, Bari, Italy.
Gaetano CitarelliSchool of Cardiology, University of Bari, Bari, Italy.
Annalisa DoronzoCardiology Department, Bari Local Health Service, Bari, Italy.
Valeria AntoncecchiCardiology Department, Bari Local Health Service, Bari, Italy.
Agata PuzzovivoCardiology Department, Bari Local Health Service, Bari, Italy.
Caterina RizzoSchool of Cardiology, University of Bari, Bari, Italy.
Maria Silvia LattaruloSchool of Cardiology, University of Bari, Bari, Italy.
Francesco MassariCardiology Department, Bari Local Health Service, Bari, Italy.
Pasquale CaldarolaCardiology Department, Bari Local Health Service, Bari, Italy.
Marco Matteo CicconeSchool of Cardiology, University of Bari, Bari, Italy.
University of Bari Aldo Moro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe renal arterial resistance index (RRI) is a Doppler measure, which reflects abnormalities in the renal blood flow. The aim of this study was to verify the value of RRI as a predictor of worsening renal function (WRF) in a group of chronic heart failure (CHF) outpatients.

methodsWe enrolled 266 patients in stable clinical conditions and on conventional therapy. Peak systolic velocity and end diastolic velocity of a segmental renal artery were obtained by pulsed Doppler flow, and RRI was calculated. Creatinine serum levels were evaluated at baseline and at 1 year, and the changes were used to assess WRF occurrence.

resultsDuring follow-up, 34 (13%) patients showed WRF. RRI was associated with WRF at univariate (OR: 1.13; 95% CI: 1.07-1.20) as well as at a forward stepwise multivariate logistic regression analysis (OR: 1.09; 95% CI: 1.03-1.16; p = 0.005) including the other univariate predictors.

conclusionsQuantification of arterial renal perfusion provides a new parameter that independently predicts the WRF in CHF outpatients. Its possible role in current clinical practice to better define the risk of cardiorenal syndrome progression is strengthened.

Indexed as

Chronic kidney diseaseGlomerular hemodynamicsSystemic disease and the kidney

Identifiers

PMID27994601
PMCPMC5159733
OpenAlexW2522226646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.