Evidence map›Paper›PMID 27994580›Full record

ArticleFrontiers in microbiology2016

Correlation of

Ivy Rukasha, Halima M Said, Shaheed V Omar, Hendrik Koornhof, Andries W Dreyer, Alfred Musekiwa, Harry Moultrie, Anwar A Hoosen, Gilla Kaplan, Dorothy Fallows and 1 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Differential Impact of theMicrobiology spectrum · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Infection and drug resistance · 2022
    Article
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ivy RukashaDepartment of Medical Microbiology, Faculty of Health Sciences, University of the Free State Bloemfontein, South Africa.
Halima M SaidDepartment of Medical Microbiology, Faculty of Health Sciences, University of the Free StateBloemfontein, South Africa; Centre for Tuberculosis, National Institute for Communicable DiseasesSandringham, South Africa.
Shaheed V OmarCentre for Tuberculosis, National Institute for Communicable Diseases Sandringham, South Africa.
Hendrik KoornhofCentre for Tuberculosis, National Institute for Communicable DiseasesSandringham, South Africa; Department of Medical Microbiology, Faculty of Health Sciences, University of the WitwatersrandJohannesburg, South Africa.
Andries W DreyerCentre for Tuberculosis, National Institute for Communicable DiseasesSandringham, South Africa; Department of Medical Microbiology, Faculty of Health Sciences, University of the WitwatersrandJohannesburg, South Africa.
Alfred MusekiwaCentre for Evidence-based Health Care, Faculty of Medicine and Health Sciences, Stellenbosch University Cape Town, South Africa.
Harry MoultrieMedical Research Council, Respiratory and Meningeal Pathogens Research Unit, School of Pathology, University of the Witwatersrand Johannesburg, South Africa.
Anwar A HoosenDepartment of Medical Microbiology, Faculty of Health Sciences, University of the Free State Bloemfontein, South Africa.
Gilla KaplanThe Bill and Melinda Gates Foundation, Seattle WA, USA.
Dorothy FallowsPublic Health Research Institute, New Jersey Medical School, The State University of New Jersey, Rutgers University, Newark NJ, USA.
Nazir IsmailCentre for Tuberculosis, National Institute for Communicable DiseasesSandringham, South Africa; Department of Medical Microbiology, Faculty of Health Sciences, University of PretoriaPretoria, South Africa.

Funding

Emerging XDR-TB: Host and Pathogen ContributionsR01AI080737 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI FALLOWS, DOROTHY A. · 2009 to 2013
$2.9M
NIAID NIH HHS R01 AI080737
6 · The paper itself

Abstract

Treatment of tuberculosis (TB) and HIV co-infections is often complicated by drug-to-drug interactions between anti-mycobacterial and anti-retroviral agents. Rifabutin (RFB) is an alternative to rifampin (RIF) for TB regimens and is recommended for HIV patients concurrently receiving protease inhibitors because of reduced induction of CYP3A4. This study sought to determine the proportion of RFB susceptible isolates among RIF-resistant strains in a high HIV prevalence setting in South Africa. In addition, the study explored the association between

Indexed as

HIV/AIDSminimum inhibitory concentrationMycobacterium tuberculosispoint mutationrifabutinrifampicinrpoBSouth Africa

Identifiers

PMID27994580
PMCPMC5136537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.