Evidence map›Paper›PMID 27994498›Full record

ArticleInternational journal of medical sciences2016

Association between survivin genetic polymorphisms and epidermal growth factor receptor mutation in non-small-cell lung cancer.

Tu-Chen Liu, Ming-Ju Hsieh, Wen-Jun Wu, Ying-Erh Chou, Whei-Ling Chiang, Shun-Fa Yang, Shih-Chi Su, Thomas Chang-Yao Tsao

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Functional significance of miR-218 in lung cancer.Journal of cancer metastasis and treatment · 2026
    Article
  3. International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Tu-Chen LiuInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Chest Medicine, Cheng-Ching General Hospital, Taichung, Taiwan.
Ming-Ju HsiehInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Cancer Research Center, Changhua Christian Hospital, Changhua, Taiwan.; Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
Wen-Jun WuInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.
Ying-Erh ChouDepartment of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.
Whei-Ling ChiangSchool of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan.
Shih-Chi SuWhole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan.
Thomas Chang-Yao TsaoSchool of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Division of Chest, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
Chung Shan Medical University · TWChung Shan Medical University Hospital · TWChang Gung Memorial Hospital · TWChanghua Christian Hospital · TWCheng Ching Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Survivin is an anti-apoptotic protein that is implicated in the regulation of apoptosis and cell cycle in various types of cancers. The current study explored the effect of

Indexed as

AdultCarcinoma, Non-Small-Cell LungErbB ReceptorsFemaleGenotypeHumansInhibitor of Apoptosis ProteinsLung NeoplasmsMaleMiddle AgedMutationPolymorphism, GeneticPolymorphism, Single NucleotideReal-Time Polymerase Chain ReactionSurvivinBIRC5 protein, humanErbB ReceptorsInhibitor of Apoptosis ProteinsSurvivinepidermal growth factor receptorgenetic variants.non-small-cell lung carcinomasurvivin

Identifiers

PMID27994498
PMCPMC5165686
OpenAlexW2565898067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.