Evidence map›Paper›PMID 27994475›Full record

ReviewInfection and drug resistance2016

Isavuconazole for the treatment of invasive aspergillosis and mucormycosis: current evidence, safety, efficacy, and clinical recommendations.

Suganthini Krishnan Natesan, Pranatharthi H Chandrasekar

Open access · goldAbstract readReview
In one paragraph

Review in Infection and drug resistance, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Challenges and opportunities in the management of severe pneumonia. Key concepts from the Seventh Annual Meeting of Spanish Experts 2025.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  3. Review
  4. Article
  5. Mucormycosis: A Rare disease to Notifiable Disease.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Review
  6. Review
  7. Article
  8. Review
  9. [Clinical features of children withNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2022
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Successful long-term therapy of mucormycosis with isavuconazole.Proceedings (Baylor University. Medical Center) · 2021
    Article
  15. Article
  16. Article
  17. Isavuconazole-Animal Data and Clinical Data.Journal of fungi (Basel, Switzerland) · 2020
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Suganthini Krishnan NatesanDivision of Infectious Diseases, Department of Internal Medicine, Wayne State University; John D Dingell VA Medical Center, Detroit, MI, USA.
Pranatharthi H ChandrasekarDivision of Infectious Diseases, Department of Internal Medicine, Wayne State University.
Wayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of invasive mold infections diagnosed in immunocompromised cancer patients include invasive aspergillosis (IA) and mucormycosis. Despite timely and effective therapy, mortality remains considerable. Antifungal agents currently available for the management of these serious infections include triazoles, polyenes, and echinocandins. Until recently, posaconazole has been the only triazole with a broad spectrum of anti-mold activity against both

Indexed as

antifungal therapyaspergillosisdrug interactionsefficacyisavuconazolemucormycosisnovel azoletolerability

Identifiers

PMID27994475
PMCPMC5153275
OpenAlexW2560360976

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.