Evidence map›Paper›PMID 27994453›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2016

Drop in lung function during asthma and COPD exacerbations - can it be assessed without spirometry?

Hasse Melbye, Salwan Al-Ani, Mark Spigt

Open access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Associations with antibiotic prescribing for acute exacerbation of COPD in primary care: secondary analysis of a randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021
    Trial
  2. Chest auscultation - tradition and expectationsScandinavian journal of primary health care · 2026
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Hasse MelbyeGeneral Practice Research Unit, Department of Community Medicine, UIT The Arctic University of Norway, Tromsø, Norway.
Salwan Al-AniGeneral Practice Research Unit, Department of Community Medicine, UIT The Arctic University of Norway, Tromsø, Norway.
Mark SpigtGeneral Practice Research Unit, Department of Community Medicine, UIT The Arctic University of Norway, Tromsø, Norway; Department of Family Medicine, CAPHRI, Maastricht University, Maastricht, the Netherlands.
UiT The Arctic University of Norway · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhen assessing patients with exacerbation of asthma or COPD, it may be useful to know the drop in forced expiratory volume in 1 second (FEV

methodsIn this prospective multicenter study from primary care, patients diagnosed with asthma or COPD were examined at stable state and during exacerbations the following year. Symptoms, chest findings, and pulse oximetry were recorded, and spirometry was performed. A fixed drop in FEV

resultsThree hundred and eighty patients attended baseline examination, and 88 with a subsequent exacerbation were included in the analysis. Thirty (34%) had a significant drop in FEV

conclusionIncreased wheezing, as experienced by the patient, and a decreased SpO

Indexed as

SpirometryAdministration, InhalationAdministration, OralAdrenal Cortex HormonesAgedAsthmaBiomarkersBronchodilator AgentsDisease ProgressionFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedNorwayAdrenal Cortex HormonesBiomarkersBronchodilator AgentsOxygenbronchial obstructiondiagnostic testsprimary caresystemic corticosteroids

Identifiers

PMID27994453
PMCPMC5153253
OpenAlexW2560551645

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.