ArticleClinical interventions in aging2016
The influence of frailty syndrome on medication adherence among elderly patients with hypertension.
Article in Clinical interventions in aging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- The influence of hypertension management on frailty prevention among older persons aged 65 and over: a systematic review.Aging clinical and experimental research · 2022Pooled it
- Global Burden, Regional Differences, Trends, and Health Consequences of Medication Nonadherence for Hypertension During 2010 to 2020: A Meta-Analysis Involving 27 Million Patients.Journal of the American Heart Association · 2022Pooled it
- Self-Reported Medication Adherence Measured With Morisky Medication Adherence Scales and Its Determinants in Hypertensive Patients Aged ≥60 Years: A Systematic Review and Meta-Analysis.Frontiers in pharmacology · 2019Pooled it
- Improvement of medication adherence in osteoporosis through telemedicine combined with email: a patient-reported experience and outcome measure-based prospective study.BMJ health & care informatics · 2025Trial
- Blood pressure satisfaction and antihypertensive medication adherence effects frailty transitions in older hypertensive patients.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- The effectiveness of motivational interviewing on self-management in older adults with hypertension and frailty: study protocol for a randomized controlled trial.Frontiers in public health · 2026Article
- Promoting Medication Adherence in the Elderly: Factors and Insights From a Cross-Sectional Study.Aging medicine (Milton (N.S.W)) · 2025Article
- Medication Use by Older Adults with Frailty: A Scoping Review.Pharmacy (Basel, Switzerland) · 2025Review
- The Influence of Frailty on Pharmacotherapy Adherence and Adverse Drug Reactions in Older Psychiatric Patients.Geriatrics (Basel, Switzerland) · 2025Article
- Barriers and Facilitators to Medication Adherence among the Vulnerable Elderly: A Focus Group Study.Healthcare (Basel, Switzerland) · 2024Article
- 2023 Guideline for the management of hypertension in the elderly population in China.Journal of geriatric cardiology : JGC · 2024Article
- The prevalence of frailty and its effect on the outcome in cardiac resynchronization therapy patients.GeroScience · 2024Article
- Frailty and Cardiovascular Outcomes in Adults With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2024Article
- Frailty syndrome and associated factors among patients with hypertension: A cross-sectional study in Kumasi, Ghana.Health science reports · 2023Article
- Frailty Assessment and Perioperative Major Adverse Cardiovascular Events After Noncardiac Surgery.The American journal of medicine · 2023Article
- Frailty and medication adherence among older adult patients with hypertension: a moderated mediation model.Frontiers in public health · 2023Article
- When blood pressure refuses to budge: exploring the complexity of resistant hypertension.Frontiers in cardiovascular medicine · 2023Review
- The Effect of Frailty Syndrome on the Quality of Life of Individuals with Parkinson's Disease: A Pilot Observational and Multicenter Study on the Polish Population.International journal of environmental research and public health · 2022Observational
- Adherence to Medication in Older Adults with Type 2 Diabetes Living in Lubuskie Voivodeship in Poland: Association with Frailty Syndrome.Journal of clinical medicine · 2022Article
- Feasibility and Reliability of Home-based Spirometry Telemonitoring in Allogeneic Hematopoietic Cell Transplant Recipients.Annals of the American Thoracic Society · 2020Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension affects about 80% of people older than 80 years; however, diagnosis and treatment are difficult because about 55% of them do not adhere to treatment recommendations due to low socioeconomic status, comorbidities, age, physical limitations, and frailty syndrome.
aimsThe purposes of this study were to evaluate the influence of frailty on medication adherence among elderly hypertensive patients and to assess whether other factors influence adherence in this group of patients. METHODS AND
resultsThe study included 296 patients (mean age 68.8±8.0) divided into frail (n=198) and non-frail (n=98) groups. The Polish versions of the Tilburg Frailty Indicator (TFI) for frailty assessment and 8-item Morisky Medication Adherence Scale for adherence assessment were used. The frail patients had lower medication adherence in comparison to the non-frail subjects (6.60±1.89 vs 7.11±1.42;
conclusionFrailty is highly prevalent among elderly hypertensive patients. Higher level of frailty among elderly patients can be considered as a determinant of lower adherence. However, social support and knowledge about complications of untreated hypertension are the most important independent determinants of adherence to pharmacological treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.