Evidence map›Paper›PMID 27994294›Full record

ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2016

Association of Beta-2 Microglobulin with Inflammation and Dislipidemia in High-Flux Membrane Hemodialysis Patients.

Valdete Topçiu-Shufta, Ramë Miftari, Valdete Haxhibeqiri, Shpend Haxhibeqiri

Open access · greenAbstract read
In one paragraph

Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
  4. Review
  5. Article
  6. AnFrontiers in molecular neuroscience · 2022
    Article
  7. Article
  8. Albuminuria and Estimated GFR as Risk Factors for Dementia in Midlife and Older Age: Findings From the ARIC Study.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Valdete Topçiu-ShuftaClinic of Medical Biochemistry, University Clinical Center, Pristina, Republic of Kosova; Faculty of Medicine, University of Prishtina, Republic of Kosova.
Ramë MiftariFaculty of Medicine, University of Prishtina, Republic of Kosova.
Valdete HaxhibeqiriClinic of Medical Biochemistry, University Clinical Center, Pristina, Republic of Kosova.
Shpend HaxhibeqiriFaculty of Medicine, University of Prishtina, Republic of Kosova.
University Clinical Center of Kosovo · XKUniversity of Prishtina · XK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHigher than expected cardiovascular mortality in hemodialysis patients, has been attributed to dyslipidemia as well as inflammation. Beta2-Microglobulin (β2M) is an independent predictor of outcome for hemodialysis patients and a representative substance of middle molecules.

resultsIn 40 patients in high-flux membrane hemodialysis, we found negative correlation of β2M with high density lipoprotein (r=-0.73, p<0.001) and albumin (r= -0.53, p<0.001) and positive correlation with triglycerides (r=0.69, p<0.001), parathyroid hormone (r=0.58, p < 0.05) and phosphorus (r= 0.53, p<0.001). There was no correlation of β2M with C- reactive protein (CRP) and interleukin-6 (IL-6). During the follow-up period of three years, 6 out of 40 patients have died from cardiovascular events.

conclusionIn high-flux membrane hemodialysis patients, we observed a significant relationship of β2M with dyslipidemia and mineral bone disorders, but there was no correlation with inflammation.

Indexed as

Renal DialysisAdultAgedbeta 2-MicroglobulinDyslipidemiasFemaleHumansInflammationKidney Failure, ChronicLipoproteins, HDLMaleMiddle AgedSerum AlbuminYoung Adultbeta 2-MicroglobulinLipoproteins, HDLSerum Albuminbeta-2 microglobulincardiovascular diseasesdyslipidemiahemodialysisinflammation

Identifiers

PMID27994294
PMCPMC5136433
OpenAlexW2541912147

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.