ArticleJournal of genetics2016
LcMKK, a MAPK kinase from Lycium chinense, confers cadmium tolerance in transgenic tobacco by transcriptional upregulation of ethylene responsive transcription factor gene.
Article in Journal of genetics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 19 citations in OpenAlex.
- Production of secondary metabolites under challenging environments: understanding functions and mechanisms of signalling molecules.Frontiers in plant science · 2025Review
- Ectopic Expression ofPlants (Basel, Switzerland) · 2024Article
- Phosphorus-Solubilizing Bacteria Enhance Cadmium Immobilization and Gene Expression in Wheat Roots to Reduce Cadmium Uptake.Plants (Basel, Switzerland) · 2024Article
- Transcription factors involved in plant responses to cadmium-induced oxidative stress.Frontiers in plant science · 2024Review
- Decoding Heavy Metal Stress Signalling in Plants: Towards Improved Food Security and Safety.Plants (Basel, Switzerland) · 2020Review
- Salicylic acid application alleviates the adverse effects of triclosan stress in tobacco plants through the improvement of plant photosynthesis and enhancing antioxidant system.Environmental science and pollution research international · 2020Article
- MicroRNA-mRNA expression profiles and their potential role in cadmium stress response in Brassica napus.BMC plant biology · 2019Article
- Functional Haplotype and eQTL Analyses of Genes Affecting Cadmium Content in Cultivated Rice.Rice (New York, N.Y.) · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cadmium (Cd) is a highly toxic element to plants. Ethylene is an important phytohormone in the regulation of plant growth, development and stress response. Mitogen-activated protein kinase (MAPK) activation has been observed in plants exposed to Cd stress and was suggested to be involved in ethylene biosynthesis. We hypothesized that there may be a link between MAPK cascades and ethylene signalling in Cd-stressed plants. To test this hypothesis, the expression of LcMKK, LchERF and LcGSH1 genes, endogenous ethylene accumulation, GSH content and Cd concentration in Lycium chinense with or without Cd stress treatment were studied. Our results showed that LcMKK gene expression can be induced by the treatment of Cd in L. chinense. The transgenic tobacco expressing 35S::LcMKK showed greater tolerance to Cd stress and enhanced expression of NtERF and NtGSH1 genes, indicating that LcMKK is associated with the enhanced expression level of ERF and GSH synthesis-related genes in tobacco. We also found that endogenous ethylene and GSH content can be induced by Cd stress in L. chinense, and inhibited by cotreatment with PD98059, an inhibitor of MAPK kinase. Evidences presented here suggest that under Cd stress, GSH accumulation occurred at least partially by enhanced LcMKK gene expression and the ethylene signal transduction pathways might be involved in this accumulation.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.