Evidence map›Paper›PMID 27993968›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2017

Mechanisms of Acquired Drug Resistance to the HDAC6 Selective Inhibitor Ricolinostat Reveals Rational Drug-Drug Combination with Ibrutinib.

Jennifer E Amengual, Sathyen A Prabhu, Maximilian Lombardo, Kelly Zullo, Paul M Johannet, Yulissa Gonzalez, Luigi Scotto, Xavier Jirau Serrano, Ying Wei, Jimmy Duong and 5 more

Abstract read
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Recent Update of HDAC Inhibitors in Lymphoma.Frontiers in cell and developmental biology · 2020
    Review
  10. Review
  11. Article
  12. Article
  13. The Therapeutic Strategy of HDAC6 Inhibitors in Lymphoproliferative Disease.International journal of molecular sciences · 2018
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jennifer E AmengualCenter for Lymphoid Malignancies, Columbia University Medical Center, New York, New York. jea2149@columbia.edu.
Sathyen A PrabhuCenter for Lymphoid Malignancies, Columbia University Medical Center, New York, New York.
Maximilian LombardoCenter for Lymphoid Malignancies, Columbia University Medical Center, New York, New York.
Kelly ZulloCenter for Lymphoid Malignancies, Columbia University Medical Center, New York, New York.
Paul M JohannetStanford University School of Medicine, Stanford, California.
Yulissa GonzalezCenter for Lymphoid Malignancies, Columbia University Medical Center, New York, New York.
Luigi ScottoCenter for Lymphoid Malignancies, Columbia University Medical Center, New York, New York.
Xavier Jirau SerranoCenter for Lymphoid Malignancies, Columbia University Medical Center, New York, New York.
Ying WeiDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York.
Jimmy DuongDepartment of Biostatistics, Mailman School of Public Health, Columbia University, New York, New York.
Renu NandakumarDivision of Clinical Pathology, Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York.
Serge CremersDivision of Clinical Pathology, Department of Pathology and Cell Biology, Columbia University Medical Center, New York, New York.
Akanksha VermaInstitute for Computational Biomedicine, Weill Cornell Medical College, New York, New York.
Olivier ElementoInstitute for Computational Biomedicine, Weill Cornell Medical College, New York, New York.
Owen A O'ConnorCenter for Lymphoid Malignancies, Columbia University Medical Center, New York, New York.

Funding

Engaging University of California Stakeholders for Biorespository ResearchUL1TR000004 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GRANDIS, JENNIFER RUBIN · 2012 to 2015
$78.0M
The identification and validation of mechanisms and biomarkers for relapse in diffuse large B-cell lymphoma (Administrative Supplement)R01CA194547 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI ELEMENTO, OLIVIER, TAM, WAYNE · 2015 to 2019
$2.6M
The joint WCM-NYGC Center for Functional and Clinical Interpretation of Tumor ProfilesU24CA210989 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI ELEMENTO, OLIVIER, ZODY, MICHAEL C · 2016 to 2020
$2.4M
NCATS NIH HHS UL1 TR000004NCI NIH HHS R01 CA194547NCI NIH HHS U24 CA210989
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdenineAnimalsAntineoplastic Combined Chemotherapy ProtocolsApoptosisCell Line, TumorDrug Resistance, NeoplasmDrug SynergismHistone Deacetylase 6Histone Deacetylase InhibitorsHumansHydroxamic AcidsLymphomaMicePiperidinesPyrazolesPyrimidinesAdenineHDAC6 protein, humanHistone Deacetylase 6Histone Deacetylase InhibitorsHydroxamic AcidsibrutinibPiperidinesPyrazolesPyrimidinesricolinostat

Identifiers

PMID27993968
PMCPMC5474138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.