Evidence map›Paper›PMID 27993942›Full record

ArticleGlycobiology2017

The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting glycan microarray-based data.

Yan Liu, Ryan McBride, Mark Stoll, Angelina S Palma, Lisete Silva, Sanjay Agravat, Kiyoko F Aoki-Kinoshita, Matthew P Campbell, Catherine E Costello, Anne Dell and 18 more

Abstract readEditorial
In one paragraph

Article in Glycobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Article
  2. SpyCEP dismantles neutrophil immunity via disorder-driven chemokine remodeling and GAG targeting.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  9. Review
  10. Article
  11. Serum antibody screening using glycan arrays.Chemical Society reviews · 2024
    Review
  12. Article
  13. Elucidating the glycan-binding specificity and structure ofBeilstein journal of organic chemistry · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Characterization of a glycan-binding complex of minor pilins completes the analysis ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. The structure of aJournal of structural biology: X · 2023
    Article
  20. High-Throughput Glycomic Methods.Chemical reviews · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors.

Yan LiuDepartment of Medicine, Glycosciences Laboratory, Imperial College London, Du Cane Road, London W12 0NN, UK.
Ryan McBrideDepartment of Cell and Molecular Biology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA.
Mark StollDepartment of Medicine, Glycosciences Laboratory, Imperial College London, Du Cane Road, London W12 0NN, UK.
Angelina S PalmaDepartment of Medicine, Glycosciences Laboratory, Imperial College London, Du Cane Road, London W12 0NN, UK.
Lisete SilvaDepartment of Medicine, Glycosciences Laboratory, Imperial College London, Du Cane Road, London W12 0NN, UK.
Sanjay AgravatDepartment of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA.
Kiyoko F Aoki-KinoshitaDepartment of Science and Engineering for Sustainable Innovation, Faculty of Science and Engineering, Soka University, 1-236 Tangimachi, Hachioji, Tokyo 192-8577, Japan.
Matthew P CampbellBiomolecular Frontiers Research Centre, Macquarie University, Sydney, NSW 2109, Australia.
Catherine E CostelloDepartment of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University, School of Medicine, 670 Albany Street, Suite 504, Boston, MA 02118, USA.
Anne DellDepartment of Life Sciences, Faculty of Natural Sciences, Imperial College London, London SW7 2AZ, UK.
Stuart M HaslamDepartment of Life Sciences, Faculty of Natural Sciences, Imperial College London, London SW7 2AZ, UK.
Niclas G KarlssonDepartment of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, PO Box 440, 405 30 Gothenburg, Sweden.
Kay-Hooi KhooInstitute of Biological Chemistry, Academia Sinica, 128, Academia Road Sec. 2, Nankang, Taipei 115, Taiwan.
Daniel KolarichDepartment of Biomolecular Systems, Max Planck Institute of Colloids and Interfaces, Potsdam 14424, Germany.
Milos V NovotnyDepartment of Chemistry, Indiana University, 800 E. Kirkwood Avenue, Bloomington, IN 47405, USA.
Nicolle H PackerBiomolecular Frontiers Research Centre, Macquarie University, Sydney, NSW 2109, Australia.
Rene RanzingerComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
Erdmann RappMax Planck Institute for Dynamics of Complex Technical Systems, Bioprocess Engineering, 39106 Magdeburg, Germany.
Pauline M RuddNIBRT GlycoScience Group, NIBRT-National Institute for Bioprocessing Research and Training, Fosters Avenue, Mount Merrion, Blackrock, Co., Dublin, Ireland.
Weston B StruweDepartment of Biochemistry, Glycobiology Institute, University of Oxford, Oxford OX1 3QU, UK.
Michael TiemeyerComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
Lance WellsComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
William S YorkComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, GA 30602, USA.
Joseph ZaiaDepartment of Biochemistry, Center for Biomedical Mass Spectrometry, Boston University, School of Medicine, 670 Albany Street, Suite 504, Boston, MA 02118, USA.
Carsten KettnerBeilstein-Institut, Trakehner Str. 7-9, 60487 Frankfurt am Main, Germany.
James C PaulsonDepartment of Cell and Molecular Biology, The Scripps Research Institute, 10550 N Torrey Pines Road, La Jolla, CA 92037, USA.
Ten FeiziDepartment of Medicine, Glycosciences Laboratory, Imperial College London, Du Cane Road, London W12 0NN, UK.
David F SmithEmory Comprehensive Glycomics Core, Emory University School of Medicine, Atlanta, GA 30322, USA.

Funding

Structural Basis of Immune Recognition of Glycosylated AntigensU54GM062116 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI SASISEKHARAN, RAM · 2001 to 2010
$80.3M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
TR&D1: Stem Cell and Induced Pluripotent Stem Cell Resources (Pages 116-134)P41GM103490 · NIGMS · UNIVERSITY OF GEORGIA · PI PIERCE, J. MICHAEL · 2012 to 2018
$13.7M
Overall Priority Score P41GM103694 · NIGMS · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D · 2013 to 2018
$6.9M
Protein-Glycan Interaction Resource of the CFGR24GM098791 · NIGMS · EMORY UNIVERSITY · PI CUMMINGS, RICHARD D, PAULSON, JAMES C · 2011 to 2013
$2.6M
NCATS NIH HHS UL1 TR000454NIGMS NIH HHS P41 GM103490NIGMS NIH HHS P41 GM103694NIGMS NIH HHS R24 GM098791NIGMS NIH HHS U54 GM062116
6 · The paper itself

Abstract

MIRAGE (Minimum Information Required for A Glycomics Experiment) is an initiative that was created by experts in the fields of glycobiology, glycoanalytics and glycoinformatics to produce guidelines for reporting results from the diverse types of experiments and analyses used in structural and functional studies of glycans in the scientific literature. As a sequel to the guidelines for sample preparation (Struwe et al. 2016, Glycobiology, 26:907-910) and mass spectrometry  data (Kolarich et al. 2013, Mol. Cell Proteomics, 12:991-995), here we present the first version of guidelines intended to improve the standards for reporting data from glycan microarray analyses. For each of eight areas in the workflow of a glycan microarray experiment, we provide guidelines for the minimal information that should be provided in reporting results. We hope that the MIRAGE glycan microarray guidelines proposed here will gain broad acceptance by the community, and will facilitate interpretation and reproducibility of the glycan microarray results with implications in comparison of data from different laboratories and eventual deposition of glycan microarray data in international databases.

Indexed as

glycan microarraysglycansglycobiologyglycomicsMIRAGE

Identifiers

PMID27993942
PMCPMC5444268

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.