ArticleResuscitation2017
ECMO Cardio-Pulmonary Resuscitation (ECPR), trends in survival from an international multicentre cohort study over 12-years.
Article in Resuscitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
111 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Concomitant Intra-Aortic Balloon Pump Throughout Extracorporeal Cardiopulmonary Resuscitation: A Meta-Analysis of Cohorts.Reviews in cardiovascular medicine · 2026Pooled it
- Extra-corporeal-cardiopulmonary-resuscitation vs. conventional-cardiopulmonary-resuscitation: an in-depth look into short- and long-term neurological outcomes.Journal of cardiothoracic surgery · 2025Pooled it
- Part 4: Systems of Care: 2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care.Circulation · 2025Guideline
- Extracorporeal membrane oxygenation for critically ill adults.The Cochrane database of systematic reviews · 2023Pooled it
- Extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest: A systematic review and meta-analysis of randomized and propensity score-matched studies.Artificial organs · 2022Pooled it
- [Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure : Short version of the S3 guideline].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2021Guideline
- [Use of extracorporeal circulation (ECLS/ECMO) for cardiac and circulatory failure : Short version of the S3 guideline].Der Anaesthesist · 2021Guideline
- The impact of selection criteria and study design on reported survival outcomes in extracorporeal oxygenation cardiopulmonary resuscitation (ECPR): a systematic review and meta-analysis.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021Pooled it
- Pooled it
- Extracorporeal cardiopulmonary resuscitation for cardiac arrest: A systematic review.Resuscitation · 2018Pooled it
- The effect of initial rhythm on patient outcome in refractory cardiac arrest requiring extracorporeal cardiopulmonary resuscitation: A retrospective, multicentre registry cohort study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- Characteristics and outcomes of younger adults with out-of-hospital cardiac arrest resuscitated with extracorporeal membrane oxygenation: a nationwide study.BMC cardiovascular disorders · 2026Observational
- Extracorporeal Membrane Oxygenation in Refractory Cardiac Arrest: Current Evidence, Clinical Pathways and Future Directions.Life (Basel, Switzerland) · 2026Review
- Costs and complications of extracorporeal membrane oxygenation therapy in Australia and New Zealand.Critical care (London, England) · 2026Observational
- Extracorporeal cardiopulmonary resuscitation in a large tertiary center in the Czech Republic: three years' experience and future directions.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Article
- Emergency total extracorporeal life support versus standard advanced cardiac life support with rescue extracorporeal membrane oxygenation for refractory out-of-hospital cardiac arrest: protocol for the ECLS-OHCA randomized trial.Scandinavian journal of trauma, resuscitation and emergency medicine · 2026Article
- Implementation of emergency extracorporeal membrane oxygenation in a hospital without on-site cardiothoracic surgery support.Resuscitation plus · 2026Article
- Eligibility for Extracorporeal Cardio-Pulmonary Resuscitation in Out-of-Hospital Cardiac Arrests in Sweden.Acta anaesthesiologica Scandinavica · 2026Article
- Extracorporeal Cardiopulmonary Resuscitation for In-Hospital Cardiac Arrest: A Single-Center Experience in Latin America.Arquivos brasileiros de cardiologia · 2026Article
- Clinical Prediction Score for Patients With Initial Nonshockable Rhythm Receiving Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest: Development and Internal Validation.Journal of the American Heart Association · 2025Observational
51 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUse of Extracorporeal Membrane Oxygenation during cardiopulmonary resuscitation (ECPR) is increasingly being deployed as an adjunct to conventional CPR. It is unknown if this has been associated with improved outcomes.
aimsTo describe trends in survival and patient demographics for ECPR patients in the international Extracorporeal Life Support Organisation (ELSO) database over the past 12 years and identify factors associated with changes in survival.
methodsPatients greater than 16 years of age who received ECPR between January 2003 and December 2014 were extracted from the ELSO registry and were divided into three 4-year cohorts (Cohort 1: 2003-2006, Cohort 2: 2007-2010, Cohort 3: 2011-2014). Univariable analysis was performed to compare demographics and outcomes of patients across the three cohorts. Univariable and multivariable analyses were then performed to identify factors independently associated with survival.
results1796 patients treated with ECPR were extracted from the registry, aged 50 (±18.5) years. Annual ECPR episodes increased over 10-fold, from 35 to over 400 per year. Survival to hospital discharge was 29% overall (27% cohort 1, 28% cohort 2, 30% cohort 3 (p=0.71)). Age, body weight and documented comorbidities increased over time. There was a reduction in complications associated with ECMO usage. After adjusting for confounders there was no change in the odds of survival over the time period examined.
interpretationOver the period 2003-2014, survival to hospital discharge was 29% for patients who require ECPR. Despite advances in provision of ECMO care and increasing co-morbidities of patients, there has been no change in risk-adjusted survival over time.
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