Evidence map›Paper›PMID 27992373›Full record

ReviewOncotarget2017

Sex chromosome abnormalities and psychiatric diseases.

Xinzhu Zhang, Jian Yang, Yuhong Li, Xin Ma, Rena Li

Open access · diamondAbstract readReview
In one paragraph

Review in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Psychotropic Medication Use in 48,XXYY Syndrome.American journal of medical genetics. Part A · 2025
    Article
  2. Article
  3. Triple X syndrome: Psychiatric disorders and impaired social functioning as a risk factor.European psychiatry : the journal of the Association of European Psychiatrists · 2022
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Genes known to escape X chromosome inactivation predict co-morbid chronic musculoskeletal pain and posttraumatic stress symptom development in women following trauma exposure.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2019
    Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Xinzhu ZhangBeijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Jian YangBeijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Beijing, China.
Yuhong LiBeijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Xin MaBeijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Rena LiBeijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
Beijing Anding Hospital · CNChinese Institute for Brain Research · CNRoskamp Institute · US

Funding

PATHOBIOLOGICAL STUDIES OF VESSEL BACE1 IN CEREBROVASCULAR AMYLOID ANGIOPATHYR01NS092610 · NINDS · ROSKAMP INSTITUTE, INC. · PI CRAWFORD, FIONA C., MULLAN, MICHAEL J · 2016 to 2020
$2.0M
The role of estrogen receptors in Alzheimer?s diseaseR01AG032441 · NIA · ROSKAMP INSTITUTE, INC. · PI LI, RENA · 2009 to 2012
$1.3M
NIA NIH HHS R01 AG032441NINDS NIH HHS R01 NS092610
6 · The paper itself

Abstract

Excesses of sex chromosome abnormalities in patients with psychiatric diseases have recently been observed. It remains unclear whether sex chromosome abnormalities are related to sex differences in some psychiatric diseases. While studies showed evidence of susceptibility loci over many sex chromosomal regions related to various mental diseases, others demonstrated that the sex chromosome aneuploidies may be the key to exploring the pathogenesis of psychiatric disease. In this review, we will outline the current evidence on the interaction of sex chromosome abnormalities with schizophrenia, autism, ADHD and mood disorders.

Indexed as

Sex Chromosome AberrationsAttention Deficit Disorder with HyperactivityAutistic DisorderChromosomes, Human, XChromosomes, Human, YFemaleGenetic Predisposition to DiseaseHumansMalePolymorphism, Single NucleotideSchizophreniaADHDautismdepressiongenderschizophrenia

Identifiers

PMID27992373
PMCPMC5354807
OpenAlexW2563289816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.