Evidence map›Paper›PMID 27991819›Full record

ArticleEmotion (Washington, D.C.)2017

Autonomic reactivity and vulnerability to depression: A multi-wave study.

Jonathan P Stange, Jessica L Hamilton, Thomas M Olino, David M Fresco, Lauren B Alloy

Open access · hybridAbstract read
In one paragraph

Article in Emotion (Washington, D.C.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Neurophysiological Markers of Regulation Success in Everyday Life in Depression.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026
    Article
  5. Article
  6. Individual-Specific Animated Profiles of Mental Health.Perspectives on psychological science : a journal of the Association for Psychological Science · 2025
    Article
  7. Review
  8. Autonomic complexity dynamically indexes affect regulation in everyday life.Journal of psychopathology and clinical science · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jonathan P StangeDepartment of Psychology, Temple University.
Jessica L HamiltonDepartment of Psychology, Temple University.
Thomas M OlinoDepartment of Psychology, Temple University.
David M FrescoDepartment of Psychology, Kent State University.
Lauren B AlloyDepartment of Psychology, Temple University.
Temple University · USKent State University · US

Funding

Mindfulness-Based Stress Reduction for High Blood Pressure: A Two-Site RCTR01HL119977 · NHLBI · KENT STATE UNIVERSITY · PI FRESCO, DAVID M · 2014 to 2018
$3.8M
Risk for Adolescent Depression: Stress, Cognitive Vulnerability, & InflammationR01MH101168 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI ALLOY, LAUREN BERSH · 2013 to 2017
$3.2M
SMART Center II Brain Behavior Connections in Self Management ScienceP30NR015326 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI MOORE, SHIRLEY M · 2014 to 2018
$2.8M
Inflexibility and Vulnerability to DepressionF31MH099761 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI STANGE, JONATHAN P · 2012 to 2014
$87k
Physiological Markers of Stress Generation and Affect Reactivity in DepressionF31MH106184 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI HAMILTON, JESSICA LEIGH · 2014 to 2015
$64k
NHLBI NIH HHS R01 HL119977NIMH NIH HHS F31 MH099761NIMH NIH HHS F31 MH106184NIMH NIH HHS R01 MH101168NINR NIH HHS P30 NR015326
6 · The paper itself

Abstract

The ability of the autonomic nervous system to flexibly adapt to environmental changes is thought to indicate efficient use of self-regulatory resources. Deficits in autonomic reactivity appear to characterize current depression; however, whether autonomic reactivity confers vulnerability to future depression when individuals encounter environmental stressors is unknown. Fluctuations in respiratory sinus arrhythmia (RSA) and heart rate (HR) were evaluated in response to emotion-eliciting films among 134 undergraduates. Negative events and depressive symptoms were assessed 5 times across 12 weeks. Multilevel modeling demonstrated that smaller decreases in RSA in response to sadness, greater increases in HR following sadness, and smaller increases in HR to amusement were prospectively associated with greater depressive symptoms when individuals encountered high levels of idiographically assessed negative events. These results demonstrate that the lack of contextually appropriate autonomic reactivity may confer vulnerability to depression under conditions of environmental stress, perhaps due to attenuated capacity for effective self-regulation. (PsycINFO Database Record

Indexed as

AdolescentAdultAgedAutonomic Nervous SystemDepressionFemaleHumansMaleMiddle AgedProspective StudiesYoung Adult

Identifiers

PMID27991819
PMCPMC5444964
OpenAlexW2563826526

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.