Evidence map›Paper›PMID 27991694›Full record

ArticleThe International journal of eating disorders2017

Characterizing severe and enduring anorexia nervosa: An empirical approach.

Jennifer E Wildes, Kelsie T Forbush, Kelsey E Hagan, Marsha D Marcus, Evelyn Attia, Loren M Gianini, Wei Wu

Abstract read
In one paragraph

Article in The International journal of eating disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Trial
  5. Clinical staging for eating disorders: A scoping review and update.European psychiatry : the journal of the Association of European Psychiatrists · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jennifer E WildesDepartment of Psychiatry and Behavioral Neuroscience, The University of Chicago, Chicago, Illinois.
Kelsie T ForbushDepartment of Psychology, University of Kansas, Lawrence, Kansas.
Kelsey E HaganDepartment of Psychology, University of Kansas, Lawrence, Kansas.
Marsha D MarcusDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Evelyn AttiaDepartment of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York.
Loren M GianiniDepartment of Psychiatry, College of Physicians and Surgeons of Columbia University, New York, New York.
Wei WuDepartment of Psychology, University of Kansas, Lawrence, Kansas.

Funding

Research Training in Biobehavioral Disturbances of Eating DisordersT32MH096679 · NIMH · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI EVELYN ATTIA, B. TIMOTHY WALSH · 2013 to 2026
$2.4M
Mood and Anxiety Subtypes in Anorexia Nervosa: Relevance to TreatmentK01MH080020 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WILDES, JENNIFER E · 2008 to 2012
$656k
NIMH NIH HHS K01 MH080020NIMH NIH HHS T32 MH096679
6 · The paper itself

Abstract

Targeted approaches for the treatment of severe and enduring anorexia nervosa (SE-AN) have been recommended, but there is no consensus definition of SE-AN to inform research and clinical practice. This study aimed to take initial steps toward developing an empirically based definition of SE-AN by characterizing associations among putative indicators of severity and chronicity in eating disorders. Patients with AN (N = 355) completed interviews and questionnaires at treatment admission and discharge; height and weight were assessed to calculate body mass index (BMI). Structural equation mixture modeling was used to test whether associations among potential indicators of SE-AN (illness duration, treatment history, BMI, binge eating, purging, quality-of-life) formed distinct subgroups, a single group with one or more dimensions, or a combination of subgroups and dimensions. A three-factor (dimensional), two-profile (categorical) mixture model provided the best fit to the data. Factor 1 included eating disorder behaviors; Factor 2 comprised quality-of-life domains; Factor 3 was characterized by illness duration, number of hospitalizations, and admission BMI. Profiles differed on eating disorder behaviors and quality-of-life, but not on indicators of chronicity or BMI. Factor scores, but not profile membership, predicted outcome at discharge from treatment. Data suggest that patients with AN can be classified on the basis of eating disorder behaviors and quality-of-life, but there was no evidence for a chronic subgroup of AN. Rather, indices of chronicity varied dimensionally within each class. Given that current definitions of SE-AN rely on illness duration, these findings have implications for research and clinical practice.

Indexed as

AdolescentAdultAnorexia NervosaBinge-Eating DisorderBody Mass IndexBody WeightBulimiaBulimia NervosaEatingFeeding BehaviorFemaleHumansMalePrognosisQuality of LifeSeverity of Illness Indexanorexia nervosachronicclassificationenduringseverestructural equation mixture modeling

Identifiers

PMID27991694
PMCPMC5386793

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.