Evidence map›Paper›PMID 27991580›Full record

ArticleScientific reports2016

Anatomically correct visualization of the human upper airway using a high-speed long range optical coherence tomography system with an integrated positioning sensor.

Joseph C Jing, Lidek Chou, Erica Su, Brian J F Wong, Zhongping Chen

Abstract read
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Optica · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Biomedical optics express · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph C JingBeckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 92617 USA.
Lidek ChouBeckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 92617 USA.
Erica SuBeckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 92617 USA.
Brian J F WongBeckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 92617 USA.
Zhongping ChenBeckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 92617 USA.

Funding

Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY · 2012 to 2017
$7.0M
Phase resolved ARF optical coherence elastography for intravascular imagingR01HL125084 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ZHOU, QIFA · 2014 to 2023
$5.6M
Modeling the Pediatric Upper Airway using A-OCT and Computational Fluid DynamicsR01HL105215 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, ELGHOBASHI, SAID E. · 2010 to 2013
$3.7M
Combined OCT/US/PAT system for intravascular ImagingR01HL127271 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI CHEN, ZHONGPING, PATEL, PRANAV · 2015 to 2018
$2.7M
High Resolution Elastograpy of Retina Under Prosthetic Electrical StimulationR01EY026091 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHEN, ZHONGPING, ZHOU, QIFA · 2016 to 2019
$2.0M
Elastographic Imaging of the Retina/Choroid in Age-Related Macular DegenerationR01EY021529 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHEN, ZHONGPING, SILVERMAN, RONALD H · 2012 to 2015
$1.4M
NEI NIH HHS R01 EY021529NEI NIH HHS R01 EY026091NHLBI NIH HHS R01 HL105215NHLBI NIH HHS R01 HL125084NHLBI NIH HHS R01 HL127271NIBIB NIH HHS P41 EB015890
6 · The paper itself

Abstract

The upper airway is a complex tissue structure that is prone to collapse. Current methods for studying airway obstruction are inadequate in safety, cost, or availability, such as CT or MRI, or only provide localized qualitative information such as flexible endoscopy. Long range optical coherence tomography (OCT) has been used to visualize the human airway in vivo, however the limited imaging range has prevented full delineation of the various shapes and sizes of the lumen. We present a new long range OCT system that integrates high speed imaging with a real-time position tracker to allow for the acquisition of an accurate 3D anatomical structure in vivo. The new system can achieve an imaging range of 30 mm at a frame rate of 200 Hz. The system is capable of generating a rapid and complete visualization and quantification of the airway, which can then be used in computational simulations to determine obstruction sites.

Indexed as

Computer SimulationHumansImaging, Three-DimensionalRespiratory SystemTomography, Optical Coherence

Identifiers

PMID27991580
PMCPMC5171831

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.