ArticleNature communications2016
Complementarity of PALM and SOFI for super-resolution live-cell imaging of focal adhesions.
Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- SPIFFI enables single-shot super-resolution and multidimensional imaging.Nature methods · 2026Article
- A series of spontaneously blinking dyes for super-resolution microscopy.Nature methods · 2026Article
- From Microscale to Nanoscale Shadow Electrochemiluminescence Microscopy.Angewandte Chemie (International ed. in English) · 2026Article
- Tensile expansion microscopy applies mechanical force to super-resolve fixed and image live cellular samples.bioRxiv : the preprint server for biology · 2026Article
- Near-isotropic super-resolution microscopy with axial interference speckle illumination.Nature communications · 2025Article
- Electrochemically controlled switching of dyes for enhanced superresolution optical fluctuation imaging (EC-SOFI).Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- SOGO-SOFI, light-modulated super-resolution optical fluctuation imaging using only 20 raw frames for high-fidelity reconstruction.Fundamental research · 2025Article
- High-Throughput Single-Molecule Microscopy with Adaptable Spatial Resolution Using Exchangeable Oligonucleotide Labels.ACS nano · 2025Article
- Super-resolution microscopy based on the inherent fluctuations of dye molecules.Biomedical optics express · 2025Article
- Article
- Measuring the Co-Localization and Dynamics of Mobile Proteins in Live Cells Undergoing Signaling Responses.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Fluorescence fluctuation-based super-resolution microscopy: Basic concepts for an easy start.Journal of microscopy · 2022Review
- Technological advances in super-resolution microscopy to study cellular processes.Molecular cell · 2022Review
- Article
- Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy.Nature communications · 2021Article
- Review
- Mechanobiology: A New Frontier in Biology.Biology · 2021Article
- Design of experiments for the optimization of SOFI super-resolution microscopy imaging.Biomedical optics express · 2021Article
- Visualization of integrin molecules by fluorescence imaging and techniques.Biocell : official journal of the Sociedades Latinoamericanas de Microscopia Electronica ... et. al · 2021Article
- Time-correlated single molecule localization microscopy enhances resolution and fidelity.Scientific reports · 2020Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Live-cell imaging of focal adhesions requires a sufficiently high temporal resolution, which remains a challenge for super-resolution microscopy. Here we address this important issue by combining photoactivated localization microscopy (PALM) with super-resolution optical fluctuation imaging (SOFI). Using simulations and fixed-cell focal adhesion images, we investigate the complementarity between PALM and SOFI in terms of spatial and temporal resolution. This PALM-SOFI framework is used to image focal adhesions in living cells, while obtaining a temporal resolution below 10 s. We visualize the dynamics of focal adhesions, and reveal local mean velocities around 190 nm min
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