Evidence map›Paper›PMID 27990708›Full record

ArticleJournal of magnetic resonance imaging : JMRI2017

Temporal accumulation and localization of isoflurane in the C57BL/6 mouse and assessment of its potential contamination in

Christakis Constantinides, Mahon L Maguire, Leeanne Stork, Edyta Swider, Mangala Srinivas, Carolyn A Carr, Jurgen E Schneider

Open access · hybridAbstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. FirstTheranostics · 2023
    Article
  6. Molecular imaging and biology · 2022
    Article
  7. Article
  8. Article
  9. Perfluorocarbons-BasedInternational journal of nanomedicine · 2020
    Review
  10. Article
  11. Article
  12. Article
  13. In vivoMagma (New York, N.Y.) · 2019
    Article
  14. In Vivo Tracking andACS applied materials & interfaces · 2018
    Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Christakis ConstantinidesDepartment of Cardiovascular Medicine, Nuffield Department of Medicine, Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands.
Mahon L MaguireDepartment of Cardiovascular Medicine, Nuffield Department of Medicine, Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands.
Leeanne StorkDepartment of Cardiovascular Medicine, Nuffield Department of Medicine, Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands.
Edyta SwiderDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom.
Mangala SrinivasDepartment of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom.
Carolyn A CarrDepartment of Tumor Immunology, Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands.
Jurgen E SchneiderDepartment of Cardiovascular Medicine, Nuffield Department of Medicine, Radboud University Medical Center, Radboud University, Nijmegen, The Netherlands.
Radboud University Medical Center · NLUniversity of Oxford · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the uptake, accumulation, temporal stability, and spatial localization of isoflurane (ISO) in the C57BL/6 mouse, and to identify its potential interference with the detection of labeled cardiac progenitor cells using MATERIALS AND

methodsObjectives are demonstrated using (a) in vitro ISO tests, (b) in vivo temporal accumulation/spatial localization C57BL/6 studies (n = 3), and (c) through injections of perfluoro-crown-ether (PFCE) labeled cardiac progenitor cells into femoral muscle areas of the murine hindlimb post-mortem (n = 1) using

resultsTwo ISO resonances were observed in vivo that correspond to the -CF

conclusionSignificant ISO accumulation was observed by LEVEL OF EVIDENCE: 1 Technical Efficacy: Stage 1 J. MAGN. RESON. IMAGING 2017;45:1659-1667.

Indexed as

ArtifactsMagnetic Resonance ImagingAnimalsCells, CulturedCell TrackingContrast MediaEthersFluorine RadioisotopesFluorocarbonsIsofluraneMaleMetabolic Clearance RateMiceMice, Inbred C57BLReproducibility of ResultsSensitivity and SpecificityContrast MediaEthersFluorine RadioisotopesFluorocarbonsIsofluraneperfluoropolyether19F MRIcell labelingcontaminationisoflurane localization

Identifiers

PMID27990708
PMCPMC5484368
OpenAlexW2566349223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.