Evidence map›Paper›PMID 27990673›Full record

ArticlePediatric dermatology2017

Trichodysplasia Spinulosa in a 7-Year-Old Boy Managed Using Physical Extraction of Keratin Spicules.

Michael Barton, Suing Lockhart, Robert Sidbury, Richard Wang, Heather Brandling-Bennett

Abstract readCase Reports
In one paragraph

Article in Pediatric dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trichodysplasia Spinulosa.Sultan Qaboos University medical journal · 2024
    Article
  2. Trichodysplasia spinulosa: a comprehensive review of the disease and its treatment.Journal of the European Academy of Dermatology and Venereology : JEADV · 2021
    Review
  3. Article
  4. Article
  5. Article
  6. The Biology and Clinical Features of Cutaneous Polyomaviruses.The Journal of investigative dermatology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Michael BartonBillings Clinic Internal Medicine Residency, Billings, Montana.
Suing LockhartPediatric Dermatology, University of Washington, Seattle, Washington.
Robert SidburyPediatric Dermatology, University of Washington, Seattle, Washington.
Richard WangUniversity of Texas Southwestern Medical Center, Dallas, Texas.
Heather Brandling-BennettPediatric Dermatology, University of Washington, Seattle, Washington.
University of Washington · USBillings Clinic · USThe University of Texas Southwestern Medical Center · US

Funding

Elucidating the Role of Akt and Keratins in Autophagy and TumorigenesisK08CA164047 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI WANG, RICHARD C · 2012 to 2016
$708k
NCI NIH HHS K08 CA164047
6 · The paper itself

Abstract

Trichodysplasia spinulosa (TS) is an uncommon skin disease characterized by a folliculocentric papular eruption and keratin spine formation, classically appearing on the central face and ears. It occurs in immunosuppressed patients and is linked to a viral etiology. Diagnostic tests including polymerase chain reaction (PCR) are available for detection of the TS-associated polyomavirus. Effective treatment options include topical cidofovir and oral valganciclovir. We present a case diagnosed using PCR with skin scrapings and treated using physical extraction of the keratin spicules. Significant improvement was noted, suggesting a safe, cost-effective treatment alternative.

Indexed as

KeratinsChildHumansMalePolyomavirus InfectionsSkin DiseasesKeratins

Identifiers

PMID27990673
PMCPMC5788291
OpenAlexW2563053094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.