Evidence map›Paper›PMID 27990369›Full record

ArticleInternational journal of ophthalmology2016

Macular changes of neuromyelitis optica through spectral-domain optical coherence tomography.

Lu Cheng, Jing Wang, Xu He, Xun Xu, Zhen-Fen Ling

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Article in International journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. The Glymphatic System (En)during Inflammation.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lu ChengDepartment of Ophthalmology, Shanghai Jiao Tong University Affiliated Shanghai First People's Hospital, Shanghai 20080, China; Shanghai Key Laboratory of Fundus Disease, Shanghai 20080, China.
Jing WangDepartment of Ophthalmology, Shanghai Jiao Tong University Affiliated Shanghai First People's Hospital, Shanghai 20080, China; Shanghai Key Laboratory of Fundus Disease, Shanghai 20080, China.
Xu HeCase Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA.
Xun XuDepartment of Ophthalmology, Shanghai Jiao Tong University Affiliated Shanghai First People's Hospital, Shanghai 20080, China; Shanghai Key Laboratory of Fundus Disease, Shanghai 20080, China.
Zhen-Fen LingDepartment of Neurology, Shanghai Jiao Tong University Affiliated Shanghai First People's Hospital, Shanghai 20080, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo evaluate the thickness of the retinal layers in the macula using spectral-domain optical coherence tomography (SD-OCT) in patients with neuromyelitis optica (NMO).

methodsSpectralis SD-OCT, utilizing automated macular layer segmentation, was performed in 26 NMO patients and 26 healthy controls. Visual function including visual field tests and pattern visual evoked potential were recorded in study subjects.

resultsForty-one eyes from 26 NMO patients and 52 eyes from 26 age- and sex-matched healthy controls were included. Besides total macular volume, peri-paipillary retinal nerve fiber layer (RNFL) thickness, the thickness of macular RNFL, ganglion cell layer (GCL) and inner plexiform layer (IPL) were also significantly reduced in NMO patients compared to those inhealthy controls (

conclusionThe study provides

Indexed as

ganglion cell lossmacular layer thicknessneuromyelitis opticaoptical coherence tomography

Identifiers

PMID27990369
PMCPMC5145094

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.