Evidence map›Paper›PMID 27990320›Full record

ArticleJournal of molecular biomarkers & diagnosis2016

High-Throughput Diagnostic Assay for a Highly Prevalent Cardiomyopathy-Associated

David Y Barefield, Thomas L Lynch, Aravindakshan Jagadeesan, Thriveni Sanagala, Sakthivel Sadayappan

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of molecular biomarkers & diagnosis, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Reevaluation of the South AsianCirculation. Genomic and precision medicine · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

David Y BarefieldDepartment of Cell and Molecular Physiology, Loyola University, Chicago, USA; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Thomas L LynchDepartment of Cell and Molecular Physiology, Loyola University, Chicago, USA.
Aravindakshan JagadeesanDepartment of Cell and Molecular Physiology, Loyola University, Chicago, USA.
Thriveni SanagalaDepartment of Cardiology and Echocardiography and Cardiographics, Loyola University, Chicago, USA.
Sakthivel SadayappanDepartment of Cell and Molecular Physiology, Loyola University, Chicago, USA.
Loyola University Chicago · USNorthwestern University · US

Funding

Fast myosin binding protein-C and cardiac contractility in heart failureR01HL105826 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2011 to 2025
$4.5M
Molecular mechanism of hypertrophic cardiomyopathy in populations of South Asian descendantsR01HL130356 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2016 to 2019
$1.6M
Proteomic approaches to validate novel cardiac biomarkers for myocardial infarctiK02HL114749 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2012 to 2016
$498k
Myosin binding protein H-like and its role in cardiomyopathyF32HL131304 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BAREFIELD, DAVID Y · 2016 to 2018
$155k
NHLBI NIH HHS F32 HL131304NHLBI NIH HHS K02 HL114749NHLBI NIH HHS R01 HL105826NHLBI NIH HHS R01 HL130356
6 · The paper itself

Abstract

A 25-basepair deletion variant of

Indexed as

DNA diagnostic testGenotype-phenotypeHypertrophic cardiomyopathyRNaseH qPCRSouth Asian population

Identifiers

PMID27990320
PMCPMC5160998
OpenAlexW2560571783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.