Evidence map›Paper›PMID 27989817›Full record

ArticleJournal of biomedical informatics2016

Evaluating common data models for use with a longitudinal community registry.

Maryam Garza, Guilherme Del Fiol, Jessica Tenenbaum, Anita Walden, Meredith Nahm Zozus

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maryam GarzaDuke Translational Medicine Institute, Duke University, 2424 Erwin Road, Hock Plaza Box 3850, Durham, NC 27705, USA. Electronic address: maryam.garza@duke.edu.
Guilherme Del FiolDepartment of Biomedical Informatics, University of Utah School of Medicine, 421 Wakara Way, Room: Suite 140, Salt Lake City, UT 84108, USA. Electronic address: guilherme.delfiol@utah.edu.
Jessica TenenbaumDepartment of Biostatistics and Bioinformatics, Duke University, 2424 Erwin Road, Suite 1102 Hock Plaza Box 2721, Durham, NC 27705, USA. Electronic address: jessie.tenenbaum@duke.edu.
Anita WaldenDuke Translational Medicine Institute, Duke University, 2424 Erwin Road, Hock Plaza Box 3850, Durham, NC 27705, USA; Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, 501 Jack Stephens Drive, Mail Slot # 782, Little Rock, AR 72205, USA. Electronic address: acwalden@uams.edu.
Meredith Nahm ZozusDepartment of Biostatistics and Bioinformatics, Duke University, 2424 Erwin Road, Suite 1102 Hock Plaza Box 2721, Durham, NC 27705, USA; Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, 501 Jack Stephens Drive, Mail Slot # 782, Little Rock, AR 72205, USA. Electronic address: mzozus@uams.edu.

Funding

Duke CTSA (Composite)UL1TR001117 · NCATS · DUKE UNIVERSITY · PI BOULWARE, LEIGH E, LI, JENNIFER S · 2013 to 2017
$41.3M
Project-003UG1DA040317 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2015 to 2019
$9.0M
Pioneering Health Information Technology (R00)R00LM011128 · NLM · UNIV OF ARKANSAS FOR MED SCIS · PI ZOZUS, MEREDITH NAHM · 2015 to 2017
$665k
NCATS NIH HHS UL1 TR001117NIDA NIH HHS UG1 DA040317NLM NIH HHS R00 LM011128
6 · The paper itself

Abstract

objectiveTo evaluate common data models (CDMs) to determine which is best suited for sharing data from a large, longitudinal, electronic health record (EHR)-based community registry. MATERIALS AND

methodsFour CDMs were chosen from models in use for clinical research data: Sentinel v5.0 (referred to as the Mini-Sentinel CDM in previous versions), PCORnet v3.0 (an extension of the Mini-Sentinel CDM), OMOP v5.0, and CDISC SDTM v1.4. Each model was evaluated against 11 criteria adapted from previous research. The criteria fell into six categories: content coverage, integrity, flexibility, ease of querying, standards compatibility, and ease and extent of implementation.

resultsThe OMOP CDM accommodated the highest percentage of our data elements (76%), fared well on other requirements, and had broader terminology coverage than the other models. Sentinel and PCORnet fell short in content coverage with 37% and 48% matches respectively. Although SDTM accommodated a significant percentage of data elements (55% true matches), 45% of the data elements mapped to SDTM's extension mechanism, known as Supplemental Qualifiers, increasing the number of joins required to query the data.

conclusionThe OMOP CDM best met the criteria for supporting data sharing from longitudinal EHR-based studies. Conclusions may differ for other uses and associated data element sets, but the methodology reported here is easily adaptable to common data model evaluation for other uses.

Indexed as

Electronic Health RecordsInformation DisseminationRegistriesBiomedical ResearchHumansCommon data modelData model evaluationElectronic health records

Identifiers

PMID27989817
PMCPMC6810649

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.