Evidence map›Paper›PMID 27989654›Full record

ReviewTrends in cell biology2017

Endocytosis, Metastasis and Beyond: Multiple Facets of SNX9.

Nawal Bendris, Sandra L Schmid

Abstract readReview
In one paragraph

Review in Trends in cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Endocytic Control of Cell-Autonomous and Non-Cell-Autonomous Functions of p53.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. RAB40C regulates SNX9 stabilityCentral-European journal of immunology · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nawal BendrisDepartment of Cell Biology, The University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: nb141@alumni.utsw.edu.
Sandra L SchmidDepartment of Cell Biology, The University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address: sandra.schmid@utsouthwestern.edu.

Funding

EARLY STEPS IN RECEPTOR-MEDIATED ENDOCYTOSISR01GM042455 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI METTLEN, MARCEL BERNARD · 1989 to 2020
$8.2M
The Clathrin Coated Vesicle CycleR01MH061345 · NIMH · UT SOUTHWESTERN MEDICAL CENTER · PI SCHMID, SANDRA L. · 2010 to 2019
$5.0M
THE CLATHRIN COATED VESICLE CYCLER37MH061345 · NIMH · SCRIPPS RESEARCH INSTITUTE, THE · PI SCHMID, SANDRA L. · 2000 to 2009
$4.7M
NIGMS NIH HHS R01 GM042455NIMH NIH HHS R01 MH061345NIMH NIH HHS R37 MH061345
6 · The paper itself

Abstract

Sorting nexin (SNX)9 was first discovered as an endocytic accessory protein involved in clathrin-mediated endocytosis. However, recent data suggest that SNX9 is a multifunctional scaffold that coordinates membrane trafficking and remodeling with changes in actin dynamics to affect diverse cellular processes. Here, we review the accumulated knowledge on SNX9 with an emphasis on its recently identified roles in clathrin-independent endocytic pathways, cell invasion, and cell division, which have implications for SNX9 function in human disease, including cancer.

Indexed as

EndocytosisAnimalsCell DivisionCell MovementDiseaseHumansNeoplasm MetastasisSorting NexinsSorting Nexinsactincancercell motilityinflammationinvadosomemitosisRhoGTPase

Identifiers

PMID27989654
PMCPMC5318277

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.