Dynamic property changes in stapedial annular ligament associated with acute otitis media in the chinchilla.

Brooke M Hitt, Xuelin Wang, Rong Z Gan

Open access · greenAbstract read

In one paragraph

Article in Medical engineering & physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.5field-weighted citation impact, top 28% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

Simulation-based inference for subject-specific tuning of middle ear finite-element models towards personalized objective diagnosis.Scientific reports · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Brooke M HittSchool of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, Norman, OK 73019, United States.

Xuelin WangSchool of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, Norman, OK 73019, United States.

Rong Z GanSchool of Aerospace and Mechanical Engineering and Biomedical Engineering Center, University of Oklahoma, Norman, OK 73019, United States. Electronic address: rgan@ou.edu.

University of Oklahoma · US

Funding

Biomechanical Measurement and Modeling of Normal and Diseased Middle EarsR01DC011585 · NIDCD · UNIVERSITY OF OKLAHOMA · PI GAN, RONG Z · 2011 to 2015

$1.7M

NIDCD NIH HHS R01 DC011585

6 · The paper itself

Abstract

Located at the end of the ossicular chain, the stapedial annular ligament (SAL) serves as a closed yet mobile boundary between the cochlear fluid and stapes footplate. It is unclear how SAL properties change with acute otitis media (AOM). This paper reports the measurements of SAL dynamic properties in chinchilla AOM model using dynamic mechanical analyzer (DMA) and frequency-temperature superposition (FTS) principle. AOM was analyzed in two infection groups: 4 days (4D) and 8 days (8D) post induction. SAL specimens were measured using DMA at three temperatures: 5, 25, and 37°C. To extend the testing frequencies to higher levels, FTS principle was employed. Then generalized Maxwell model was utilized to define the constitutive equations of the SAL. The complex shear moduli were obtained from seven samples of control, 4D, and 8D groups. Results show that the storage and loss shear moduli of SALs decreased due to AOM. The storage moduli for 4D and 8D ears were similar below 100Hz, and the loss modulus for 4D was significantly larger than 8D across the entire frequency range. This study reports data that contributes to ear biomechanics and improves understanding on the effects of AOM in middle ear tissues.

Indexed as

LigamentsMechanical PhenomenaOtitis MediaStapesAcute DiseaseAnimalsBiomechanical PhenomenaChinchillaShear StrengthTemperatureAcute otitis mediaChinchillaComplex modulusDynamic mechanical analyzerFrequency-temperature superpositionStapedial annular ligament

Identifiers

PMID27989383

DOI10.1016/j.medengphy.2016.12.003

PMCPMC5292076

OpenAlexW2560882775

What OpenQuestion holds

Textmetadata

LicenceTDM

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.