Evidence map›Paper›PMID 27989264›Full record

ReviewPublic health nutrition2017

Study sponsorship and the nutrition research agenda: analysis of randomized controlled trials included in systematic reviews of nutrition interventions to address obesity.

Alice Fabbri, Nicholas Chartres, Gyorgy Scrinis, Lisa A Bero

Abstract readReview
In one paragraph

Review in Public health nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A framework for assessing the trustworthiness of scientific research findings.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  12. Scientific rigor and credibility in the nutrition research landscape.The American journal of clinical nutrition · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alice Fabbri1Centre of Research in Medical Pharmacology,University of Insubria,Varese,Italy.
Nicholas Chartres2Charles Perkins Centre and Faculty of Pharmacy,The University of Sydney,Camperdown NSW 2006,Australia.
Gyorgy Scrinis3Faculty of Veterinary and Agricultural Sciences,The University of Melbourne,Parkville,VIC,Australia.
Lisa A Bero2Charles Perkins Centre and Faculty of Pharmacy,The University of Sydney,Camperdown NSW 2006,Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo categorize the research topics covered by a sample of randomized controlled trials (RCT) included in systematic reviews of nutrition interventions to address obesity; to describe their funding sources; and to explore the association between funding sources and nutrition research topics.

designCross-sectional study. SUBJECTS: RCT included in Cochrane Reviews of nutrition interventions to address obesity and/or overweight.

resultsTwo hundred and thirteen RCT from seventeen Cochrane Reviews were included. Funding source and authors' conflicts of interest were disclosed in 82·6 and 29·6 % of the studies, respectively. RCT were more likely to test an intervention to manipulate nutrients in the context of reduced energy intake (44·2 % of studies) than food-level (11·3 %) and dietary pattern-level (0·9 %) interventions. Most of the food industry-sponsored studies focused on interventions involving manipulations of specific nutrients (66·7 %). Only 33·1 % of the industry-funded studies addressed dietary behaviours compared with 66·9 % of the non-industry-funded ones (P=0·002). The level of food processing was poorly considered across all funding sources.

conclusionsThe predominance of RCT examining nutrient-specific questions could limit the public health relevance of rigorous evidence available for systematic reviews and dietary guidelines.

Indexed as

Conflict of InterestDietFood HandlingFood IndustryHumansNutritional SciencesNutrition AssessmentObesityOverweightRandomized Controlled Trials as TopicResearch DesignBiasNutrition interventionObesityResearch agendaSponsorship

Identifiers

PMID27989264
PMCPMC10261365

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.