Evidence map›Paper›PMID 27988890›Full record

ArticleEuropean radiology2017

Diagnostic accuracy of contemporary multidetector computed tomography (MDCT) for the detection of lumbar disc herniation.

S Notohamiprodjo, R Stahl, M Braunagel, P M Kazmierczak, K M Thierfelder, K M Treitl, S Wirth, M Notohamiprodjo

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Virtual non-calcium dual-energy CT: clinical applications.European radiology experimental · 2021
    Review
  12. Article
  13. A Noninvasive Assistant System in Diagnosis of Lumbar Disc Herniation.Computational and mathematical methods in medicine · 2020
    Article
  14. Article
  15. Current concepts for lumbar disc herniation.International orthopaedics · 2019
    Review
  16. Article
  17. Lumbar Disc Herniation.Current reviews in musculoskeletal medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

S NotohamiprodjoInstitute for Clinical Radiology, University Hospital of Munich, LMU Munich, Nussbaumstr. 20, 80336, Munich, Germany. Susan.Notohamiprodjo@med.lmu.de.ORCID http://orcid.org/0000-0002-1312-1245
R StahlInstitute for Clinical Radiology, University Hospital of Munich, LMU Munich, Nussbaumstr. 20, 80336, Munich, Germany.
M BraunagelInstitute for Clinical Radiology, University Hospital of Munich, LMU Munich, Nussbaumstr. 20, 80336, Munich, Germany.
P M KazmierczakInstitute for Clinical Radiology, University Hospital of Munich, LMU Munich, Nussbaumstr. 20, 80336, Munich, Germany.
K M ThierfelderInstitute for Clinical Radiology, University Hospital of Munich, LMU Munich, Nussbaumstr. 20, 80336, Munich, Germany.
K M TreitlInstitute for Clinical Radiology, University Hospital of Munich, LMU Munich, Nussbaumstr. 20, 80336, Munich, Germany.
S WirthInstitute for Clinical Radiology, University Hospital of Munich, LMU Munich, Nussbaumstr. 20, 80336, Munich, Germany.
M NotohamiprodjoDiagnostic and Interventional Radiology, University Hospital Tübingen, Eberhard Karls University Tübingen, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the diagnostic accuracy of multidetector CT (MDCT) for detection of lumbar disc herniation with MRI as standard of reference.

methodsPatients with low back pain underwent indicated MDCT (128-row MDCT, helical pitch), 60 patients with iterative reconstruction (IR) and 67 patients with filtered back projection (FBP). Lumbar spine MRI (1.5 T) was performed within 1 month. Signal-to-noise ratios (SNR) of cerebrospinal fluid (CSF), annulus fibrosus (AF) and the spinal cord (SC) were determined for all modalities. Two readers independently rated image quality (IQ), diagnostic confidence and accuracy in the diagnosis of lumbar disc herniation using MRI as standard of reference. Inter-reader correlation was assessed with weighted κ.

resultsSensitivity, specificity, precision and accuracy of MDCT for disc protrusion were 98.8%, 96.5%, 97.1%, 97.8% (disc level), 97.7%, 92.9%, 98.6%, 96.9% (patient level). SNR of IR was significantly higher than FBP. IQ was significantly better in IR owing to visually reduced noise and improved delineation of the discs. κ (>0.90) was excellent for both algorithms.

conclusionMDCT of the lumbar spine yields high diagnostic accuracy for detection of lumbar disc herniation. IR improves image quality so that the provided diagnostic accuracy is principally equivalent to MRI. KEY POINTS: • MDCT is an accurate alternative to MRI in disc herniation diagnosis. • By IR enhanced image quality improves MDCT diagnostic confidence similar to MRI. • Advances in CT technology contribute to improved diagnostic performance in lumbar spine imaging.

Indexed as

AdultAgedAged, 80 and overAlgorithmsFemaleHumansIntervertebral Disc DisplacementLow Back PainLumbar VertebraeMagnetic Resonance ImagingMaleMiddle AgedMultidetector Computed TomographyRadiculopathyRetrospective StudiesSensitivity and SpecificityDisc prolapseMagnetic resonance imagingMultidetector computed tomographyNerve root compressionSciatica

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.