Evidence map›Paper›PMID 27988859›Full record

ReviewFamilial cancer2017

ATM mutations for surgeons.

Sara A Mansfield, Robert Pilarski, Doreen M Agnese

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Familial cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. A novel mutation inPakistan journal of medical sciences · 2024
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sara A MansfieldDepartment of General Surgery, The Ohio State University College of Medicine, Columbus, OH, USA.
Robert PilarskiDepartment of Internal Medicine, James Comprehensive Cancer Center, The Ohio State University College of Medicine, Columbus, OH, USA.
Doreen M AgneseDivision of Surgical Oncology, Department of Surgery, The Ohio State University College of Medicine, N908 Doan Hall, 410 W 10th Ave, Columbus, OH, 43210, USA. Doreen.agnese@osumc.edu.
The Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ataxia-telangiectasia mutated (ATM) gene encodes a protein kinase involved in DNA repair. Heterozygotic carriers are at an increased risk of developing breast cancer. As the use of genetic testing increases, identification of at-risk patients will also increase. The aim of this study is to review two cases of heterozygous ATM mutation carriers and review the literature to clarify the cancer risks and suggested management for breast surgeons who will be intimately involved in the care of these patients.

Indexed as

AdultAtaxia Telangiectasia Mutated ProteinsBreast NeoplasmsFemaleGenetic Predisposition to DiseaseHeterozygoteHumansMiddle AgedMutationSurgeonsAtaxia Telangiectasia Mutated ProteinsATM protein, humanAtaxia-telangiectasia mutationBreast cancerGenetic screening

Identifiers

PMID27988859
OpenAlexW2563269331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.