Evidence map›Paper›PMID 27988858›Full record

ArticleJournal of biomolecular NMR2016

Sequence-specific assignment of methyl groups from the neuronal SNARE complex using lanthanide-induced pseudocontact shifts.

Yun-Zu Pan, Bradley Quade, Kyle D Brewer, Monika Szabo, James D Swarbrick, Bim Graham, Josep Rizo

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biomolecular NMR, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Yun-Zu PanDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Bradley QuadeDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Kyle D BrewerDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Monika SzaboMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.
James D SwarbrickMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.
Bim GrahamMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.
Josep RizoDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA. Jose.Rizo-Rey@UTSouthwestern.edu.
The University of Texas Southwestern Medical Center · USMonash University · AU

Funding

Mechanisms of neurotransmitter release and its regulationR35NS097333 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2017 to 2024
$7.0M
STRUCTURE/FUNCTION OF SYNTAXIN 1R01NS037200 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 1998 to 2016
$6.5M
Molecular Biophysics Predoctoral Training ProgramT32GM008297 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI CHOOK, YUH MIN · 1989 to 2018
$2.4M
Acquisition of upgrades for 800 MHz NMR consoleS10OD018027 · OD · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2014 to 2014
$376k
600MHz Varian VNMRS Console UpgradeS10RR026461 · NCRR · UT SOUTHWESTERN MEDICAL CENTER · PI ROSEN, MICHAEL K · 2010 to 2010
$254k
NCRR NIH HHS S10 RR026461NIGMS NIH HHS T32 GM008297NIH HHS S10 OD018027NINDS NIH HHS R01 NS037200NINDS NIH HHS R35 NS097333
6 · The paper itself

Abstract

Neurotransmitter release depends critically on the neuronal SNARE complex formed by syntaxin-1, SNAP-25 and synaptobrevin, as well as on other proteins such as Munc18-1, Munc13-1 and synaptotagmin-1. Although three-dimensional structures are available for these components, it is still unclear how they are assembled between the synaptic vesicle and plasma membranes to trigger fast, Ca

Indexed as

Magnetic Resonance SpectroscopyNeuronsNuclear Magnetic Resonance, BiomolecularAnimalsIsotope LabelingLanthanoid Series ElementsMultiprotein ComplexesRatsSNARE ProteinsLanthanoid Series ElementsMultiprotein ComplexesSNARE ProteinsMembrane fusionMethyl assignmentNeurotransmitter releasePseudocontact shiftsSNAREs

Identifiers

PMID27988858
PMCPMC5216067
OpenAlexW2566386624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.