Evidence map›Paper›PMID 27988269›Full record

ArticleAmerican journal of obstetrics and gynecology2017

Assessment of vulvar discomfort with sexual activity among women in the United States.

Kathryn E Flynn, Jeanne Carter, Li Lin, Stacy T Lindau, Diana D Jeffery, Jennifer Barsky Reese, Bethanee J Schlosser, Kevin P Weinfurt

Abstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kathryn E FlynnCenter for Patient Care and Outcomes Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI. Electronic address: kflynn@mcw.edu.
Jeanne CarterDepartments of Surgery and Psychiatry, Memorial Sloan Kettering Cancer Center, New York, NY.
Li LinDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Stacy T LindauDepartments of Obstetrics-Gynecology and Medicine-Geriatrics, University of Chicago, Chicago, IL.
Diana D JefferyDefense Health Agency, Department of Defense-Health Affairs, Falls Church, VA.
Jennifer Barsky ReeseCancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA; Department of Social and Behavioral Sciences, College of Public Health, Temple University, Philadelphia, PA.
Bethanee J SchlosserDepartments of Dermatology and Obstetrics-Gynecology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Kevin P WeinfurtDuke Clinical Research Institute, Duke University School of Medicine, Durham, NC; Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8M
Validating and Extending the PROMIS Sexual Function Measure for Clinical ResearchU01AR052186 · NIAMS · DUKE UNIVERSITY · PI WEINFURT, KEVIN P · 2004 to 2013
$9.5M
NCI NIH HHS P30 CA006927NCI NIH HHS P30 CA008748NIAMS NIH HHS U01 AR052186
6 · The paper itself

Abstract

backgroundMultidimensional self-report measures of sexual function for women do not include the assessment of vulvar discomfort, limiting our understanding of its prevalence. In an effort to improve the measurement of patient-reported health, the National Institutes of Health funded the creation of the Patient Reported Outcomes Measurement Information System (PROMIS). This included the development of the PROMIS Sexual Function and Satisfaction measure, and version 2.0 of the Sexual Function and Satisfaction measure included 2 scales to measure vulvar discomfort with sexual activity.

objectivesThe objectives of the study were to describe the development of 2 self-reported measures of vulvar discomfort with sexual activity, describe the relationships between these scales and scales for lubrication and vaginal discomfort, and report the prevalence of vulvar discomfort with sexual activity in a large, nationally representative sample of US women. STUDY

designWe followed PROMIS measure development standards, including qualitative development work with patients and clinicians and psychometric evaluation of candidate items based on item response theory, in a probability sample of 1686 English-speaking US adult women. We tested 16 candidate items on vulvar discomfort. We present descriptive statistics for these items, correlation coefficients among the vulvar and vaginal scales, and mean PROMIS scores with 95% confidence intervals separately by menopausal status for the 1046 women who reported sexual activity in the past 30 days.

resultsBased on the psychometric evaluation of the candidate items, we created 2 separate 4 item scales, one to measure labial discomfort and pain and one to measure clitoral discomfort and pain. Additional items not included in the scales assess pain quality, numbness, and bleeding. The correlations between the lubrication, vaginal discomfort, and the 2 vulvar discomfort measures ranged from 0.46 to 0.77, suggesting that these measures represent related yet distinct concepts. In our nationally representative sample, 1 in 5 US women endorsed some degree of vulvar discomfort with sexual activity in the past 30 days. Menopausal status was associated with lower lubrication and higher vaginal discomfort but not with vulvar discomfort.

conclusionThe PROMIS Vulvar Discomfort with Sexual Activity-Labial and Vulvar Discomfort with Sexual Activity-Clitoral scales are publicly available for use in research and clinical settings. There is limited overlap between vulvar discomfort and lubrication or vaginal discomfort. The importance of measuring vulvar discomfort as part of a comprehensive assessment of sexual function is underscored by its prevalence.

Indexed as

AdolescentAdultCervix MucusFemaleHumansMenopauseMiddle AgedPainPatient Reported Outcome MeasuresPerimenopausePsychometricsSelf ReportSexual BehaviorSurveys and QuestionnairesUnited StatesVaginadyspareuniaPatient Reported Outcomes Measurement Information System Sexual Function and Satisfaction measuresexual dysfunctionvulvar painwomen

Identifiers

PMID27988269
PMCPMC5376372

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.