ArticleExperimental gerontology2017
Allostatic load and pain severity in older adults: Results from the English Longitudinal Study of Ageing.
Article in Experimental gerontology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 44 citations in OpenAlex.
- Comorbid Conditions of Ehlers-Danlos Syndromes and Vulvodynia: A Latent Class Analysis.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2026Article
- The complexity of pain in osteoarthritis.Nature reviews. Rheumatology · 2026Review
- The association between health-related quality of life and the meaning of life in community-dwelling older adults.BMC geriatrics · 2026Article
- Article
- Exploring the relationship between allostatic load and osteoarthritis: A cross-sectional analysis from the North West Adelaide Health Study.Osteoarthritis and cartilage open · 2025Article
- Using fast periodic visual stimulation to investigate the processing of health-related images in the human brain.Scientific reports · 2025Article
- Disparities in Allostatic Load Among Different Races: A Comprehensive Scoping Review.Journal of racial and ethnic health disparities · 2025Review
- Using intensive longitudinal assessment to study mechanisms of the Native American pain inequity among persons experiencing depression and/or anxiety: The role of interpersonal discrimination and stress.The journal of pain · 2025Article
- Article
- More than chronic pain: behavioural and psychosocial protective factors predict lower brain age in adults with/at risk of knee osteoarthritis over two years.Brain communications · 2025Article
- Frailty detection with routine blood tests using data from the english longitudinal study of ageing (ELSA).European geriatric medicine · 2024Article
- Biomarker-Based Analysis of Pain in Patients with Tick-Borne Infections before and after Antibiotic Treatment.Antibiotics (Basel, Switzerland) · 2024Article
- Allostatic load and chronic pain: a prospective finding from the national survey of midlife development in the United States, 2004-2014.BMC public health · 2024Article
- Life course socioeconomic status, chronic pain, and the mediating role of allostatic load: findings from the midlife in the United States.Frontiers in public health · 2024Article
- Elucidating individual differences in chronic pain and whole person health with allostatic load biomarkers.Brain, behavior, & immunity - health · 2023Article
- Breastfeeding at Any Cost? Adverse Effects of Breastfeeding Pain on Mother-Infant Behavior.Biology · 2023Article
- The mediating effect of allostatic load on the association between life course socioeconomic disadvantage and chronic pain: a prospective finding from the National Survey of Midlife Development in the United States.Frontiers in pain research (Lausanne, Switzerland) · 2023Article
- Allostatic load and risk of hearing impairment.Brain, behavior, & immunity - health · 2022Article
- Vulnerable Dispositional Traits and Chronic Pain: Predisposing but not Predetermining.The journal of pain · 2022Article
- An objective metric of individual health and aging for population surveys.Population health metrics · 2022Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Pain is common in older adults, is frequently experienced as stressful, and is associated with increased morbidity and mortality. Stress regulatory systems are adaptive to challenge and change, allostasis, until demands exceed the adaptive capacity contributing to dysregulation, resulting in a high allostatic load. A high allostatic load is associated with increased risk of morbidity and mortality. Pain severity, based on the average intensity of frequent pain, was hypothesized to be positively associated with AL. Four formulations of AL were investigated. Cross-sectional data from Wave 4 (2008-2009) of the English Longitudinal Study of Aging (ELSA) were analyzed. Covariates in the model included age, sex, education, smoking status, alcohol consumption, activity level, depression and common comorbid health conditions. A total of 5341 individuals were included; mean age 65.3(±9.2) years, 55% female, 62.4% infrequent or no pain, 12.6% mild pain, 19.1% moderate pain, and 5.9% severe pain. Severe pain was associated with greater AL defined by all four formulations. The amount of variance explained by pain severity and the covariates was highest when allostatic load was defined by the high risk quartile (12.9%) and by the clinical value (11.7%). Findings indicate a positive relationship between pain severity and AL. Further investigation is needed to determine if there is a specific AL signature for pain that differs from other health conditions.
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Registered trials
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