Evidence map›Paper›PMID 27987650›Full record

ArticleValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research2016

Psychometric Properties of the Four-Item Morisky Green Levine Medication Adherence Scale among Atherosclerosis Risk in Communities (ARIC) Study Participants.

Hadi Beyhaghi, Bryce B Reeve, Jo E Rodgers, Sally C Stearns

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Article in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.

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32citing papers in PubMed, 2 pooled it
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1 · What the graph read from it

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3 · Its place in the literature

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32 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Hadi BeyhaghiDepartment of Health Policy and Management, Gillings School of Global Public Health, the University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address: beyhaghi@live.unc.edu.
Bryce B ReeveDepartment of Health Policy and Management, Gillings School of Global Public Health, the University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Cecil G. Sheps Center for Health Services Research, the University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jo E RodgersDivision of Pharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, the University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Sally C StearnsDepartment of Health Policy and Management, Gillings School of Global Public Health, the University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Cecil G. Sheps Center for Health Services Research, the University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

NHLBI NIH HHS HHSN268201100005CNHLBI NIH HHS HHSN268201100005GNHLBI NIH HHS HHSN268201100005INHLBI NIH HHS HHSN268201100006CNHLBI NIH HHS HHSN268201100007CNHLBI NIH HHS HHSN268201100007INHLBI NIH HHS HHSN268201100008CNHLBI NIH HHS HHSN268201100008INHLBI NIH HHS HHSN268201100009CNHLBI NIH HHS HHSN268201100009INHLBI NIH HHS HHSN268201100010CNHLBI NIH HHS HHSN268201100011CNHLBI NIH HHS HHSN268201100011INHLBI NIH HHS HHSN268201100012C
6 · The paper itself

Abstract

objectivesTo evaluate the reliability and factorial validity of the four-item Morisky Green Levine Medication Adherence Scale (MGLS) among Atherosclerosis Risk in Communities (ARIC) Study participants.

methodsWe used the cross-sectional visit 5 data from the ARIC Study to assess the measurement properties of the MGLS. We measured the internal consistency using Cronbach α (where α > 0.70 is considered reliable for group-level measurement), the response frequency, and the inter item correlation. Factor analysis of the MGLS and five other adherence items in the survey was conducted using a polychoric correlation matrix to examine the dimensionality that underlies the MGLS. A vanishing tetrad test was conducted to assess conformity with an effect indicator model.

resultsAmong the ARIC visit 5 participants, 6,261 (96%) responded to the MGLS and other questions related to medication adherence in the survey (mean age 76 ± 5 years, 59% women). The Cronbach α for the MGLS was 0.47. The inter-item correlations ranged from 0.11 to 0.26. In the factor analysis of the medication adherence survey questions, a three-factor solution was used. One factor captured the extent of nonadherence, whereas other factors focused on the reasons for nonadherence. The MGLS items spread out across the factors that reflect the extent of as well as the reasons for nonadherence. The results of the vanishing tetrad test indicated that the MGLS consists of items other than effect indicators (P < 0.0001).

conclusionsThe low reliability together with the factor analysis findings imply that the MGLS may reflect causes as well as the extent of medication adherence. The findings suggest that the MGLS, as presently used, lacks consistency in an elderly population.

Indexed as

Drug MonitoringAgedAged, 80 and overAnticholesteremic AgentsCardiovascular AgentsCross-Sectional StudiesFemaleHumansHypoglycemic AgentsMaleMedication AdherenceMiddle AgedPolypharmacyPsychometricsReproducibility of ResultsResidence CharacteristicsAnticholesteremic AgentsCardiovascular AgentsHypoglycemic Agentscausal indicatoreffect indicatorfactorial validitymedication adherencereliability

Identifiers

PMID27987650
PMCPMC5287458

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.