Evidence map›Paper›PMID 27987032›Full record

ArticleWorld journal of urology2017

Zero hospital admissions for infection after 577 transperineal prostate biopsies using single-dose cephazolin prophylaxis.

Lana Pepdjonovic, Guan Hee Tan, Sean Huang, Sarah Mann, Mark Frydenberg, Daniel Moon, Uri Hanegbi, Adam Landau, Ross Snow, Jeremy Grummet

Abstract read
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In one paragraph

Article in World journal of urology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. [Perineal prostate biopsy].Urologie (Heidelberg, Germany) · 2024
    Review
  9. Article
  10. Review
  11. Landmarks in the evolution of prostate biopsy.Nature reviews. Urology · 2023
    Review
  12. Success of targeted transperineal biopsy in patients on surveillance for grade group 1 prostate cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2022
    Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Lana PepdjonovicAustralian Urology Associates, Melbourne, VIC, Australia. lanapep@gmail.com.
Guan Hee TanUrology Unit, Department of Surgery, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.
Sean HuangAustralian Urology Associates, Melbourne, VIC, Australia.
Sarah MannAustralian Urology Associates, Melbourne, VIC, Australia.
Mark FrydenbergAustralian Urology Associates, Melbourne, VIC, Australia.
Daniel MoonAustralian Urology Associates, Melbourne, VIC, Australia.
Uri HanegbiAustralian Urology Associates, Melbourne, VIC, Australia.
Adam LandauAustralian Urology Associates, Melbourne, VIC, Australia.
Ross SnowAustralian Urology Associates, Melbourne, VIC, Australia.
Jeremy GrummetAustralian Urology Associates, Melbourne, VIC, Australia.
Alfred Health · AUMonash University · AUNational University of Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the rate of hospital admissions for infection after transperineal biopsy of prostate (TPB) with single-dose cephazolin prophylaxis using a prospective database.

methodBetween April 2013 and February 2016, 577 patients undergoing TPB had 2 g of cephazolin given intravenously at induction of anaesthesia. Data collected from these patients included age, PSA, prostate volume, number of cores taken and post-operative complications.

resultsNo patients were readmitted to hospital with infection post-TPB. Seven patients developed acute urinary retention, and one patient developed clinical prostatitis that was treated with oral antibiotics in the community.

conclusionIt is safe to use single-dose cephazolin only as antibiotic prophylaxis prior to TPB, negating the need for quinolones. This study supports Australia's current Therapeutic Guidelines recommendation for TPB prophylaxis and the existing evidence that sepsis post-TPB is a rare complication. Whether any antibiotic prophylaxis is needed at all for TPB is the subject of a future study.

Indexed as

AdultAgedAged, 80 and overAnti-Bacterial AgentsAntibiotic ProphylaxisBiopsy, Large-Core NeedleCefazolinDatabases, FactualHospitalizationHumansMaleMiddle AgedPatient ReadmissionPerineumPostoperative ComplicationsProstateAnti-Bacterial AgentsCefazolinAntibiotic prophylaxisCephazolinProstateTransperineal biopsy

Identifiers

PMID27987032
OpenAlexW2564116626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.