Evidence map›Paper›PMID 27986896›Full record

ArticleThe Plant cell2017

easyGWAS: A Cloud-Based Platform for Comparing the Results of Genome-Wide Association Studies.

Dominik G Grimm, Damian Roqueiro, Patrice A Salomé, Stefan Kleeberger, Bastian Greshake, Wangsheng Zhu, Chang Liu, Christoph Lippert, Oliver Stegle, Bernhard Schölkopf and 2 more

Abstract read
In one paragraph

Article in The Plant cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

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  5. TheProceedings of the National Academy of Sciences of the United States of America · 2026
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  10. Enhancing genomic prediction inFrontiers in bioinformatics · 2025
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  20. Predicting Gene Regulatory Interactions Using Natural Genetic Variation.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Dominik G GrimmMachine Learning and Computational Biology Research Group, Max Planck Institute for Intelligent Systems and Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany dominik.grimm@bsse.ethz.ch karsten.borgwardt@bsse.ethz.ch.ORCID 0000-0003-2085-4591
Damian RoqueiroDepartment for Biosystems Science and Engineering, ETH Zürich, 4058 Basel, Switzerland.
Patrice A SaloméDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Stefan KleebergerMachine Learning and Computational Biology Research Group, Max Planck Institute for Intelligent Systems and Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Bastian GreshakeMachine Learning and Computational Biology Research Group, Max Planck Institute for Intelligent Systems and Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.ORCID 0000-0002-9925-9623
Wangsheng ZhuDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Chang LiuDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.ORCID 0000-0001-6363-2556
Christoph LippertMachine Learning and Computational Biology Research Group, Max Planck Institute for Intelligent Systems and Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Oliver StegleMachine Learning and Computational Biology Research Group, Max Planck Institute for Intelligent Systems and Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.
Bernhard SchölkopfDepartment of Empirical Inference, Max Planck Institute for Intelligent Systems, 72076 Tübingen, Germany.
Detlef WeigelDepartment of Molecular Biology, Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany.ORCID 0000-0002-2114-7963
Karsten M BorgwardtMachine Learning and Computational Biology Research Group, Max Planck Institute for Intelligent Systems and Max Planck Institute for Developmental Biology, 72076 Tübingen, Germany dominik.grimm@bsse.ethz.ch karsten.borgwardt@bsse.ethz.ch.ORCID 0000-0001-7221-2393

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ever-growing availability of high-quality genotypes for a multitude of species has enabled researchers to explore the underlying genetic architecture of complex phenotypes at an unprecedented level of detail using genome-wide association studies (GWAS). The systematic comparison of results obtained from GWAS of different traits opens up new possibilities, including the analysis of pleiotropic effects. Other advantages that result from the integration of multiple GWAS are the ability to replicate GWAS signals and to increase statistical power to detect such signals through meta-analyses. In order to facilitate the simple comparison of GWAS results, we present easyGWAS, a powerful, species-independent online resource for computing, storing, sharing, annotating, and comparing GWAS. The easyGWAS tool supports multiple species, the uploading of private genotype data and summary statistics of existing GWAS, as well as advanced methods for comparing GWAS results across different experiments and data sets in an interactive and user-friendly interface. easyGWAS is also a public data repository for GWAS data and summary statistics and already includes published data and results from several major GWAS. We demonstrate the potential of easyGWAS with a case study of the model organism

Indexed as

Polymorphism, Single NucleotideArabidopsisComputational BiologyFlowersGenome, PlantGenome-Wide Association StudyGenotypeHumansPhenotypeReproducibility of ResultsSoftwareUser-Computer Interface

Identifiers

PMID27986896
PMCPMC5304348

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.