Evidence map›Paper›PMID 27986511›Full record

ArticleThe Journal of allergy and clinical immunology2017

Anaphylaxis after zoster vaccine: Implicating alpha-gal allergy as a possible mechanism.

Cosby A Stone, Jonathan A Hemler, Scott P Commins, Alexander J Schuyler, Elizabeth J Phillips, R Stokes Peebles, John M Fahrenholz

Abstract readCase ReportsLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The adverse reactions to vaccines practice parameter 10 years on-what have we learned?Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Guideline
  2. Review
  3. Review
  4. Unusual Causes of Food-Induced Anaphylaxis - A Review.Indian dermatology online journal · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Idiopathic Anaphylaxis? Analysis of Data from the Anaphylaxis Registry for West Pomerania Province, Poland.International journal of environmental research and public health · 2022
    Article
  18. Anaphylaxis to Excipients in Current Clinical Practice: Evaluation and Management.Immunology and allergy clinics of North America · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Cosby A StoneDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn. Electronic address: cosby.a.stone@vanderbilt.edu.
Jonathan A HemlerDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
Scott P ComminsDivision of Rheumatology, Allergy & Immunology, Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC.
Alexander J SchuylerAsthma and Allergic Disease Center, Carter Immunology Center, Department of Medicine, University of Virginia Health System, Charlottesville, Va.
Elizabeth J PhillipsDivision of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tenn; Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tenn; Institute for Immunology & Infectious Diseases, Murdoch University, Murdoch, Australia.
R Stokes PeeblesDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn; Allergy and Immunology Section, Medical Service, Veterans Administration Medical Center, Tennessee Valley Healthcare System, Nashville, Tenn.
John M FahrenholzDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn; Allergy and Immunology Section, Medical Service, Veterans Administration Medical Center, Tennessee Valley Healthcare System, Nashville, Tenn.

Funding

Tennessee CFAR: Implementation of Culturally Responsive Trauma-Informed Care with Youth with HIV in Memphis, TNP30AI110527 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Carolyn Audet · 2015 to 2026
$27.5M
Understanding and preventing HLA-associated drug reactionsP50GM115305 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PHILLIPS, ELIZABETH · 2015 to 2019
$13.0M
Understanding alpha-gal red meat allergyR01AI135049 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Scott Palmer Commins · 2018 to 2026
$5.1M
The Structural and Functional Basis of HLA-associated Drug HypersensitivityR01AI103348 · NIAID · UNIVERSITY OF FLORIDA · PI OSTROV, DAVID A · 2013 to 2016
$1.5M
Delayed anaphylaxis to beef and pork: mechanisms and causes of a new food allergyR21AI087985 · NIAID · UNIVERSITY OF VIRGINIA · PI COMMINS, SCOTT PALMER, PLATTS-MILLS, THOMAS A. · 2010 to 2011
$422k
Delayed Anaphylaxis to Mammalian Meat caused by IgE Ab to alpha-galR56AI113095 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI COMMINS, SCOTT PALMER · 2014 to 2014
$390k
NIAID NIH HHS P30 AI110527NIAID NIH HHS R01 AI103348NIAID NIH HHS R01 AI135049NIAID NIH HHS R21 AI087985NIAID NIH HHS R56 AI113095NIGMS NIH HHS P50 GM115305
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AllergensAnaphylaxisDrug-Related Side Effects and Adverse ReactionsEmergency Medical ServicesEpinephrineExcipientsFemaleGalactoseGelatinHerpes Zoster VaccineHumansHypersensitivityImmunity, HeterologousImmunoglobulin EMiddle AgedAllergensEpinephrineExcipientsGalactoseGelatinHerpes Zoster VaccineImmunoglobulin E

Identifiers

PMID27986511
PMCPMC5420485

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.