ArticleResuscitation2017
Incidence, characteristics, and survival following cardiopulmonary resuscitation in the quaternary neonatal intensive care unit.
Article in Resuscitation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Survival of pediatric patients after cardiopulmonary resuscitation for in-hospital cardiac arrest: a systematic review and meta-analysis.Italian journal of pediatrics · 2021Pooled it
- Cardiopulmonary resuscitation with synchronized ventilation versus 3:1 compression to ventilation ratio in a neonatal porcine model.Resuscitation plus · 2026Article
- Chest compression synchronized ventilation versus chest compression superimposed by sustained inflation in asphyxiated newborn piglets: a randomized animal trial.Intensive care medicine experimental · 2026Article
- Chest compression superimposed with sustained inflation - translating preclinical findings into a neonatal clinical trial.Resuscitation plus · 2026Article
- Chest compression during sustained inflation versus 3:1 compression-to-ventilation ratio during neonatal cardiopulmonary resuscitation of asphyxiated piglets.Resuscitation plus · 2025Article
- Resuscitation after birth and beyond in the neonatal intensive care unit: NRP or PALS?Journal of perinatology : official journal of the California Perinatal Association · 2025Review
- Chest Compression Superimposed with Sustained Inflation or 3:1 Compression/Ventilation Ratio During Neonatal Cardiopulmonary Resuscitation in the Delivery Room: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2025Review
- Utility of do-not-resuscitate orders for critically ill infants in the NICU.Pediatric research · 2025Article
- Trends, risk factors, and outcomes of unplanned extubation in a neonatal intensive care unit: a seven-year retrospective study.Frontiers in pediatrics · 2025Article
- Resuscitation education for NICU providers: Current practice and recommendations for NRP and PALS in the NICU.Seminars in perinatology · 2024Review
- Optimal oxygen use in neonatal advanced cardiopulmonary resuscitation-a literature review.Pediatric medicine (Hong Kong, China) · 2023Article
- Pulseless electrical activity and asystolic cardiac arrest in infants: identifying factors that influence outcomes.Journal of perinatology : official journal of the California Perinatal Association · 2022Article
- Simulation-Based Training in High-Quality Cardiopulmonary Resuscitation Among Neonatal Intensive Care Unit Providers.Frontiers in pediatrics · 2022Article
- Post-cardiac arrest physiology and management in the neonatal intensive care unit.Resuscitation · 2021Article
- Randomised trial of epinephrine dose and flush volume in term newborn lambs.Archives of disease in childhood. Fetal and neonatal edition · 2021Article
- Epidemiology and outcomes of infants after cardiopulmonary resuscitation in the neonatal or pediatric intensive care unit from a national registry.Resuscitation · 2021Observational
- Quality of neonatal resuscitation in Ethiopia: implications for the survival of neonates.BMC pediatrics · 2020Article
- Use of Intraosseous Vascular Access During Neonatal Resuscitation at a Tertiary Center.Frontiers in pediatrics · 2020Article
- Epinephrine in Neonatal Resuscitation.Children (Basel, Switzerland) · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundThe contemporary characteristics and outcomes of cardiopulmonary resuscitation (CPR) in the neonatal intensive care unit (NICU) are poorly described. The objectives of this study were to determine the incidence, interventions, and outcomes of CPR in a quaternary referral NICU.
methodsRetrospective observational study of infants who received chest compressions for resuscitation in the Children's Hospital of Philadelphia NICU between April 1, 2011 and June 30, 2015. Patient, event, and survival characteristics were abstracted from the medical record and the hospital-wide resuscitation database. The primary outcome was survival to hospital discharge. Univariable and multivariable analyses were performed to identify patient and event factors associated with survival to discharge.
resultsThere were 1.2 CPR events per 1000 patient days. CPR was performed in 113 of 5046 (2.2%) infants admitted to the NICU during the study period. The median duration of chest compressions was 2min (interquartile range 1, 6min). Adrenaline was administered in 34 (30%) CPR events. Of 113 infants with at least one CPR event, 69 (61%) survived to hospital discharge. Factors independently associated with decreased survival to hospital discharge were inotrope treatment prior to CPR (adjusted Odds Ratio [aOR] 0.14, 95% Confidence Interval [CI] 0.04, 0.54), and adrenaline administration during CPR (aOR 0.14, 95% CI 0.04, 0.50).
conclusionsAlthough it was not uncommon, the incidence of CPR was low (<3%) among infants hospitalized in a quaternary referral NICU. Infants receiving inotropic therapy prior to CPR and adrenaline administration during CPR were less likely to survive to hospital discharge.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.