ArticleThe ISME journal2017
Helminth burden and ecological factors associated with alterations in wild host gastrointestinal microbiota.
Article in The ISME journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 62 citations in OpenAlex.
- The dual role of intestinal parasites in shaping human gut microbiota: distinguishing helminthic and protozoan dynamics.Gut pathogens · 2026Review
- Challenging the paradigm: the Asian fish tapeworm (Schyzocotyle acheilognathi, Yamaguti 1934) lacks an intrinsic symbiotic bacterial community.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Spatial modeling of soil-transmitted helminthiases in Colombia under climate change scenariosBiomedica : revista del Instituto Nacional de Salud · 2025Article
- Eco-epidemiology of gastrointestinal parasitic infections in captive chimpanzees in Gabon.International journal for parasitology. Parasites and wildlife · 2025Article
- Noninvasive Methods Unveil the Trophic Transmission of the TapewormEcology and evolution · 2024Article
- Evaluation of anthelminthic and antiprotozoal activity of myrrh (Helminthologia · 2024Article
- Fecal microbiota of the synanthropic golden jackal (Canis aureus).Animal microbiome · 2023Article
- The gut microbiota contributes to changes in the host immune response induced by Trichinella spiralis.PLoS neglected tropical diseases · 2023Article
- Species interactions, stability, and resilience of the gut microbiota - Helminth assemblage in horses.iScience · 2023Article
- Dysbiosis of fish gut microbiota is associated with helminths parasitism rather than exposure to PAHs at environmentally relevant concentrations.Scientific reports · 2022Article
- Interactions between parasitic helminths and gut microbiota in wild tropical primates from intact and fragmented habitats.Scientific reports · 2021Article
- Intestinal parasites in rural communities in Nan Province, Thailand: changes in bacterial gut microbiota associated with minute intestinal fluke infection.Parasitology · 2020Article
- Effect of intestinal tapeworms on the gut microbiota of the common carp, Cyprinus carpio.Parasites & vectors · 2019Article
- You are what you eat: diet, health and the gut microbiota.Nature reviews. Gastroenterology & hepatology · 2019Review
- Extreme rainfall affects assembly of the root-associated fungal community.The New phytologist · 2018Article
- Effects of urbanization on the foraging ecology and microbiota of the generalist seabird Larus argentatus.PloS one · 2018Article
- The Immune and Non-Immune Pathways That Drive Chronic Gastrointestinal Helminth Burdens in the Wild.Frontiers in immunology · 2018Article
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infection by gastrointestinal helminths of humans, livestock and wild animals is common, but the impact of such endoparasites on wild hosts and their gut microbiota represents an important overlooked component of population dynamics. Wild host gut microbiota and endoparasites occupy the same physical niche spaces with both affecting host nutrition and health. However, associations between the two are poorly understood. Here we used the commonly parasitized European shag (Phalacrocorax aristotelis) as a model wild host. Forty live adults from the same colony were sampled. Endoscopy was employed to quantify helminth infection in situ. Microbiota from the significantly distinct proventriculus (site of infection), cloacal and faecal gastrointestinal tract microbiomes were characterised using 16S rRNA gene-targeted high-throughput sequencing. We found increasingly strong associations between helminth infection and microbiota composition progressing away from the site of infection, observing a pronounced dysbiosis in microbiota when samples were partitioned into high- and low-burden groups. We posit this dysbiosis is predominately explained by helminths inducing an anti-inflammatory environment in the proventriculus, diverting host immune responses away from themselves. This study, within live wild animals, provides a vital foundation to better understand the mechanisms that underpin the three-way relationship between helminths, microbiota and hosts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.