Evidence map›Paper›PMID 27982729›Full record

ArticleEpigenetics2017

Differential DNA methylation and PM

Lingzhen Dai, Amar Mehta, Irina Mordukhovich, Allan C Just, Jincheng Shen, Lifang Hou, Petros Koutrakis, David Sparrow, Pantel S Vokonas, Andrea A Baccarelli and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Epigenetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Review
  6. Association between low-concentration PMFrontiers in public health · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Associations between long-term exposures to airborne PMEnvironmental health : a global access science source · 2022
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Lingzhen Daia Department of Environmental Health , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Amar Mehtaa Department of Environmental Health , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Irina Mordukhovicha Department of Environmental Health , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Allan C Justb Department of Preventive Medicine , Icahn School of Medicine at Mount Sinai , New York , NY , USA.
Jincheng Shenc Department of Biostatistics , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Lifang Houd Department of Preventive Medicine , Feinberg School of Medicine, Northwestern University , Chicago , IL , USA.
Petros Koutrakisa Department of Environmental Health , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
David Sparrowe Veterans Affairs Normative Aging Study, Veterans Affairs Boston Healthcare System , Department of Medicine, Boston University School of Medicine , Boston , MA , USA.
Pantel S Vokonase Veterans Affairs Normative Aging Study, Veterans Affairs Boston Healthcare System , Department of Medicine, Boston University School of Medicine , Boston , MA , USA.
Andrea A Baccarellia Department of Environmental Health , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Joel D Schwartza Department of Environmental Health , Harvard T.H. Chan School of Public Health , Boston , MA , USA.
Harvard University · USVA Boston Healthcare System · USIcahn School of Medicine at Mount Sinai · USNorthwestern University · US

Funding

Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniela E Matei · 1993 to 2026
$153.9M
True Metal fac coreP30ES009089 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MATTHEW S PERZANOWSKI · 1998 to 2026
$44.7M
The Mount Sinai Transdisciplinary Center on Early Environmental ExposuresP30ES023515 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Robert O Wright · 2014 to 2026
$21.3M
Prenatal Exposure to Endocrine Disrupters, DNA Methylation, and Childhood ObesityR00ES023450 · NIEHS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI JUST, ALLAN C. · 2016 to 2018
$747k
Prenatal Exposure to Endocrine Disrupters, DNA Methylation, and Childhood ObesityK99ES023450 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI JUST, ALLAN C. · 2014 to 2015
$163k
NCI NIH HHS P30 CA060553NIEHS NIH HHS K99 ES023450NIEHS NIH HHS P30 ES009089NIEHS NIH HHS P30 ES023515NIEHS NIH HHS R00 ES023450
6 · The paper itself

Abstract

Although there is growing evidence that exposure to ambient particulate matter is associated with global DNA methylation and gene-specific methylation, little is known regarding epigenome-wide changes in DNA methylation in relation to particles and, especially, particle components. Using the Illumina Infinium HumanMethylation450 BeadChip, we examined the relationship between one-year moving averages of PM

Indexed as

DNA MethylationEpigenesis, GeneticAgedAged, 80 and overFemaleGenome-Wide Association StudyHumansMaleMetalsNuclear ProteinsParticulate MatterMetalsNuclear ProteinsParticulate MatterSLFN11 protein, humanAmbient particulate matterDNA methylationepigenome-wide association studymetalspathway enrichment

Identifiers

PMID27982729
PMCPMC5330435
OpenAlexW2561278299

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.