ArticleJournal of clinical hypertension (Greenwich, Conn.)2017
Kidney volume and ambulatory blood pressure in children.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Total Kidney Volume, Hypertension, and Deterioration of Kidney Function in Children with Early-Stage ADPKD.Journal of clinical medicine · 2025Article
- Noninvasive assessment of pediatric glomerular disease: multimodal ultrasound.Quantitative imaging in medicine and surgery · 2025Article
- The effects ofJournal of developmental origins of health and disease · 2021Article
- Renal size and cardiovascular risk in prepubertal children.Scientific reports · 2019Article
- Primary Pediatric Hypertension: Current Understanding and Emerging Concepts.Current hypertension reports · 2017Review
- Kidney volume and ambulatory blood pressure in children.Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Low nephron number has been shown to be a risk factor for hypertension (HTN) in adulthood. Kidney volume may serve as a surrogate marker for nephron mass. The relationship between kidney volume and ambulatory blood pressure (BP) in the pediatric population is not known. A retrospective chart review of children younger than 21 years who were evaluated for HTN was performed. Twenty-four-hour BP and ultrasonography data were obtained. Multiple regression was used to examine associations between BP and kidney volume. Of 84 children (mean age 13.87 years, 72.6% males), 54 had HTN. Systolic BP index during the awake, sleep, and 24-hour periods (all P≤.05) was found to be positively correlated with total kidney volume. Greater total kidney volume was found to be a positive predictor of 24-hour and sleep systolic index (P≤.05). It failed to serve as a predictor of HTN, pre-HTN, or white-coat HTN. Contrary to expectation, total kidney volume was positively associated with systolic BP indices.
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