ArticleScientific reports2016
High maltose sensitivity of sweet taste receptors in the Japanese macaque (Macaca fuscata).
Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Anatomy and dietary specialization influence sensory behaviour among sympatric primates.Proceedings. Biological sciences · 2022Article
- Salivary alpha-amylase enzyme is a non-invasive biomarker of acute stress in Japanese macaques (Macaca fuscata).Primates; journal of primatology · 2019Article
- Atomistic mechanisms underlying the activation of the G protein-coupled sweet receptor heterodimer by sugar alcohol recognition.Scientific reports · 2019Article
- Taste responsiveness of Western chimpanzees (Pan troglodytes verus) to five food-associated saccharides.Primates; journal of primatology · 2019Article
- Functional decline of sweet taste sensitivity of colobine monkeys.Primates; journal of primatology · 2018Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
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Abstract
Taste sensitivity differs among animal species depending on feeding habitat. To humans, sucrose is one of the sweetest natural sugars, and this trait is expected to be similar in other primates. However, previous behavioral tests have shown that some primate species have equal preferences for maltose and sucrose. Because sweet tastes are recognized when compounds bind to the sweet taste receptor Tas1R2/Tas1R3, we evaluated the responses of human and Japanese macaque Tas1R2/Tas1R3 to various natural sugars using a heterologous expression system. Human Tas1R2/Tas1R3 showed high sensitivity to sucrose, as expected; however, Japanese macaque Tas1R2/Tas1R3 showed equally high sensitivity to maltose and sucrose. Furthermore, Japanese macaques showed equally high sensitivity to sucrose and maltose in a two-bottle behavioral experiment. These results indicate that Japanese macaques have high sensitivity to maltose, and this sensitivity is directly related to Tas1R2/Tas1R3 function. This is the first molecular biological evidence that for some primate species, sucrose is not the most preferable natural sugar, as it is for humans.
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