ArticleNature communications2016
A TNFRSF14-FcɛRI-mast cell pathway contributes to development of multiple features of asthma pathology in mice.
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Article in Nature communications, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
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Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
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- Multi-Ancestry Epigenome-Wide Meta-Analysis Identifies Novel Bulk and Cell-Type-Specific Epigenetic Markers of Asthma with Severe Exacerbations.medRxiv : the preprint server for health sciences · 2026Article
- Immunologic comparison of alpha-gal sensitized and non-sensitized groups from a community based sample.Frontiers in immunology · 2026Article
- Impact of Gestational Maternal SARS-CoV-2 Infection on Neonatal Inflammatory Biomarkers.Research square · 2025Article
- Elucidating the dynamic tumor microenvironment through deep transcriptomic analysis and therapeutic implication of MRE11 expression patterns in hepatocellular carcinoma.Cancer cell international · 2025Article
- Aberrant Activation of Mast Cells: Molecular Mechanisms and Targets for Intervention.Clinical reviews in allergy & immunology · 2025Review
- Article
- Impact of TNF and IL-33 Cytokines on Mast Cells in Neuroinflammation.International journal of molecular sciences · 2024Review
- Adjuvant-independent airway sensitization and infection mouse models leading to allergic asthma.Frontiers in allergy · 2024Review
- A Deficiency in the Cytokine TNFSF14/LIGHT Limits Inflammation and Remodeling in Murine Eosinophilic Esophagitis.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- Realigning the LIGHT signaling network to control dysregulated inflammation.The Journal of experimental medicine · 2022Article
- HES5-mediated repression of LIGHT transcription may contribute to apoptosis in hepatocytes.Cell death discovery · 2021Article
- Dissecting Abdominal Aortic Aneurysm Is Aggravated by Genetic Inactivation of LIGHT (TNFSF14).Biomedicines · 2021Article
- Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice.Nature communications · 2021Article
- Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype.Gastroenterology · 2020Article
- Lymph node fibroblastic reticular cells deposit fibrosis-associated collagen following organ transplantation.The Journal of clinical investigation · 2020Article
- Accelerator or Brake: Immune Regulators in Malaria.Frontiers in cellular and infection microbiology · 2020Review
- PDE3 Inhibition Reduces Epithelial Mast Cell Numbers in Allergic Airway Inflammation and Attenuates Degranulation of Basophils and Mast Cells.Frontiers in pharmacology · 2020Article
- A Transcriptomic Insight into the Impact of Colon Cancer Cells on Mast Cells.International journal of molecular sciences · 2019Article
- Hematopoietic cell-derived RELMα regulates hookworm immunity through effects on macrophages.Journal of leukocyte biology · 2018Article
Corrections and comments
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Authors and funding
14 authors at 5 institutions in 4 countries.
Riccardo SibilanoDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Nicolas GaudenzioDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Marianne K DeGorterDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Laurent L ReberDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Joseph D HernandezDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Philipp M StarklDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Oliwia W ZurekDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Mindy TsaiDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Sonja ZahnerDivision of Developmental Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.
Stephen B MontgomeryDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Axel RoersInstitute for Immunology, Technische Universität Dresden, Dresden 01307, Germany.
Mitchell KronenbergDivision of Developmental Immunology, La Jolla Institute for Allergy and Immunology, La Jolla, California 92037, USA.
Mang YuDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Stephen J GalliDepartment of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA.
Stanford University · USStanford Medicine · USLa Jolla Institute for Immunology · USCeMM Research Center for Molecular Medicine · ATTU Dresden · DE
Funding
Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1MMOLECULAR &CELLULAR IMMUNOBIOLOGYT32AI007290 · NIAID · STANFORD UNIVERSITY · PI Sean Curtis Bendall, Olivia M Martinez · 1985 to 2026
$27.0MStanford Center for Clinical and Translational Education and Research (SCCTER)UL1UL1RR025744 · NCRR · STANFORD UNIVERSITY · PI GREENBERG, HARRY BERNARD · 2008 to 2011
$22.4MTracking allergen specific T cells in multi-food allergyU19AI104209 · NIAID · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2013 to 2025
$17.3MThe role of LIGHT in Colitis PathogenesisR01AI061516 · NIAID · LA JOLLA INSTITUTE FOR IMMUNOLOGY · PI KRONENBERG, MITCHELL · 2004 to 2015
$4.5MRabGEF1 in MyD88 signaling, skin immunity, and atopic dermatitisR01AR067145 · NIAMS · STANFORD UNIVERSITY · PI GALLI, STEPHEN JOSEPH · 2015 to 2019
$1.9MNeutrophils as therapeutic targets in cryopyrin-associated periodic syndromeK99AI110645 · NIAID · STANFORD UNIVERSITY · PI REBER, LAURENT LIONEL · 2014 to 2014
$130kAustrian Science Fund FWF J 3399NCATS NIH HHS UL1 TR001085NCRR NIH HHS UL1 RR025744NIAID NIH HHS K99 AI110645NIAID NIH HHS R01 AI061516NIAID NIH HHS T32 AI007290NIAID NIH HHS U19 AI104209NIAMS NIH HHS R01 AR067145
Abstract
Asthma has multiple features, including airway hyperreactivity, inflammation and remodelling. The TNF superfamily member TNFSF14 (LIGHT), via interactions with the receptor TNFRSF14 (HVEM), can support T
Indexed as
Airway RemodelingAnimalsAntibodiesAntigens, DermatophagoidesAsthmaBronchoalveolar Lavage FluidFemaleGene Expression RegulationGenotypeImmunoglobulin EImmunoglobulin GMast CellsMiceMice, KnockoutOvalbuminReceptors, IgEAntibodiesAntigens, DermatophagoidesImmunoglobulin EImmunoglobulin GOvalbuminReceptors, IgEReceptors, Tumor Necrosis Factor, Member 14Tnfrsf14 protein, mouse
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.