Evidence map›Paper›PMID 27981669›Full record

ArticleAddiction (Abingdon, England)2017

Alcohol use disorder and divorce: evidence for a genetic correlation in a population-based Swedish sample.

Jessica E Salvatore, Sara Larsson Lönn, Jan Sundquist, Paul Lichtenstein, Kristina Sundquist, Kenneth S Kendler

Abstract readTwin Study
In one paragraph

Article in Addiction (Abingdon, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Family Genetic-Risk Profiles Associated With Divorce.Clinical psychological science : a journal of the Association for Psychological Science · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Alcohol use disorder, psychiatric comorbidities, marriage and divorce in a high-risk sample.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2022
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. The gene-editing of super-ego.Medicine, health care, and philosophy · 2018
    Article
  17. Article
  18. Article
  19. Article
  20. Alcohol Misuse Across the Lifespan: Insights from Developmental Studies in Behavior Genetics.Policy insights from the behavioral and brain sciences · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Jessica E SalvatoreDepartment of Psychology, Virginia Commonwealth University, Richmond, VA, USA.
Sara Larsson LönnCenter for Primary Health Care Research, Lund University, Malmö, Sweden.
Jan SundquistCenter for Primary Health Care Research, Lund University, Malmö, Sweden.
Paul LichtensteinDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Kristina SundquistCenter for Primary Health Care Research, Lund University, Malmö, Sweden.
Kenneth S KendlerVirginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA.

Funding

Social, Developmental and Genetic Epidemiology of Alcohol Use DisordersR01AA023534 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN, SUNDQUIST, KRISTINA · 2015 to 2023
$4.0M
Genetics, Romantic Relationships, and Alcohol Misuse in Emerging AdulthoodK01AA024152 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI SALVATORE, JESSICA E · 2016 to 2020
$741k
NIAAA NIH HHS K01 AA024152NIAAA NIH HHS R01 AA023534
6 · The paper itself

Abstract

aimsWe tested the association between alcohol use disorder (AUD) and divorce; estimated the genetic and environmental influences on divorce; estimated how much genetic and environmental influences accounted for covariance between AUD and divorce; and estimated latent genetic and environmental correlations between AUD and divorce. We tested sex differences in these effects.

designWe identified twin and sibling pairs with AUD and divorce information in Swedish national registers. We described the association between AUD and divorce using tetrachorics and used twin and sibling models to estimate genetic and environmental influences on divorce, on the covariance between AUD and divorce and the latent genetic and environmental correlations between AUD and divorce.

settingSweden.

participantsA total of 670 836 individuals (53% male) born 1940-1965. MEASUREMENTS: Life-time measures of AUD and divorce.

findingsAUD and divorce were related strongly (males: r

conclusionsDivorce and alcohol use disorder are correlated strongly in the Swedish population, and the heritability of divorce is consistent with previous studies. Covariation between AUD and divorce results from overlapping genetic and non-shared environmental factors. Latent genetic and non-shared environmental correlations for alcohol use disorder and divorce are high and moderate.

Indexed as

Gene-Environment InteractionRegistriesAgedAlcoholismDivorceEnvironmentFemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedRisk FactorsSiblingsSwedenTwins, DizygoticTwins, MonozygoticAlcohol use disorderdivorcegenetic correlationheritabilitynonshared environmental correlationtwin modeling

Identifiers

PMID27981669
PMCPMC5339032

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.