Evidence map›Paper›PMID 27981378›Full record

ArticleInternational journal of colorectal disease2017

The RIPASA score is sensitive and specific for the diagnosis of acute appendicitis in a western population.

Muhammad Usman Malik, Tara M Connelly, Faisal Awan, Frederik Pretorius, Constantino Fiuza-Castineira, Osama El Faedy, Paul Balfe

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03169114 (Raja Isteri Pengiran Anak Saleha Appendicitis Treatment Without Operation - Antibiotic Non-operative Management Strategy Versus Surgery Management Strategy, a Non-Inferiority Randomised Controlled Trial.), which is not on this map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03169114 naterminatednot on this map

Raja Isteri Pengiran Anak Saleha Appendicitis Treatment Without Operation - Antibiotic Non-operative Management Strategy Versus Surgery Management Strategy, a Non-Inferiority Randomised Controlled Trial.

TypeinterventionalSponsorRaja Isteri Pengiran Anak Saleha HospitalRan2017 to 2020Enrolled81ConditionsAppendicitis, SurgeryArmsAmikacin Injection, Appendicectomy
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

  1. Pooled it
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  3. Comparison of the effectiveness of RIPASA and modified Alvarado scores in identifying perforated appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Muhammad Usman MalikDepartment of Surgery, St. Luke's Hospital, Kilkenny, Ireland.
Tara M ConnellyDepartment of Surgery, University Hospital Waterford, Waterford, Ireland. tarconnelly@rcsi.ie.
Faisal AwanDepartment of Surgery, St. Luke's Hospital, Kilkenny, Ireland.
Frederik PretoriusDepartment of Surgery, St. Luke's Hospital, Kilkenny, Ireland.
Constantino Fiuza-CastineiraDepartment of Surgery, St. Luke's Hospital, Kilkenny, Ireland.
Osama El FaedyDepartment of Surgery, St. Luke's Hospital, Kilkenny, Ireland.
Paul BalfeDepartment of Surgery, St. Luke's Hospital, Kilkenny, Ireland.
St. Luke's General Hospital · IESt. Luke's Hospital · IEUniversity Hospital Waterford · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe definitive diagnosis of acute appendicitis (AA) requires histopathological examination. Various clinical diagnostic scoring systems attempt to reduce negative appendectomy rates. The most commonly used in Western Europe and the USA is the Alvarado score. The Raja Isteri Pengiran Anak Saleha appendicitis (RIPASA) score achieves better sensitivity and specificity in Asian and Middle Eastern populations. We aimed to determine the diagnostic accuracy of the RIPASA score in Irish patients with AA.

methodsAll patients who presented to our institution with right iliac fossa pain and clinically suspected AA between January 1 and December 31, 2015, were indentified from our hospital inpatient enquiry database and retrospectively studied. Operating theatre records and histology reports confirmed those who underwent a non-elective operative procedure and the presence or absence of AA. SPSS version 22 was used for statistical analysis. Standard deviation is provided where appropriate.

resultsTwo hundred eight patients were included in the study (106/51% male, mean age 22.7 ± 9.2 years). One hundred thirty-five (64.9%) had histologically confirmed AA (mean symptom duration = 36.19 ± 15.90 h). At a score ≥7.5, the previously determined score most likely associated with AA in Eastern populations, the RIPASA scoring system demonstrated a sensitivity of 85.39%, specificity of 69.86%, positive predictive value of 84.06%, negative predictive value of 72.86% and diagnostic accuracy of 80% in our cohort.

conclusionThe RIPASA score is a useful tool to aid in the diagnosis of acute appendicitis in the Irish population. A score of ≥7.5 provides sensitivity and specificity exceeding that previously documented for the Alvarado score in Western populations. WHAT DOES THIS PAPER ADD TO THE LITERATURE?: This is the first study evaluating the utility of the RIPASA score in predicting acute appendicitis in a Western population. At a value of 7.5, a cut-off score suggestive of appendicitis in the Eastern population, RIPASA demonstrated a high-sensitivity, specificity, positive predictive value and diagnostic accuracy in our cohort and was more accurate than the commonly used Alvarado score.

Indexed as

Acute DiseaseAdolescentAdultAge DistributionAppendicitisChildCohort StudiesEuropeFemaleHospitalizationHumansMaleMiddle AgedPredictive Value of TestsSensitivity and SpecificityYoung AdultAcute appendicitisAlvarado scoreHistopathologyRaja Isteri Pengiran Anak Saleha appendicitis scoreRIPASA score

Identifiers

PMID27981378
OpenAlexW2562139721

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.