Evidence map›Paper›PMID 27981364›Full record

ArticlePflugers Archiv : European journal of physiology2017

Synergistic interplay of Gβγ and phosphatidylinositol 4,5-bisphosphate dictates Kv7.4 channel activity.

Oleksandr V Povstyan, Vincenzo Barrese, Jennifer B Stott, Iain A Greenwood

Abstract read
In one paragraph

Article in Pflugers Archiv : European journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Identification of Sodium/Myo-Inositol Transporter 1 as a Major Determinant of Arterial Contractility.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
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  12. The Kv7 Channel and Cardiovascular Risk Factors.Frontiers in cardiovascular medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Oleksandr V PovstyanVascular Biology Research Centre, Molecular and Clinical Sciences Institute, St George's, University of London, London, SW17 0RE, UK.
Vincenzo BarreseVascular Biology Research Centre, Molecular and Clinical Sciences Institute, St George's, University of London, London, SW17 0RE, UK.
Jennifer B StottVascular Biology Research Centre, Molecular and Clinical Sciences Institute, St George's, University of London, London, SW17 0RE, UK.
Iain A GreenwoodVascular Biology Research Centre, Molecular and Clinical Sciences Institute, St George's, University of London, London, SW17 0RE, UK. grenwood@sgul.ac.uk.

Funding

British Heart Foundation PG/12/63/29824British Heart Foundation PG/14/57/30992British Heart Foundation PG/15/97/31862Medical Research Council MR/K019074/1
6 · The paper itself

Abstract

Kv7.4 channels are key determinants of arterial contractility and cochlear mechanosensation that, like all Kv7 channels, have an obligatory requirement for phosphatidylinositol 4,5-bisphosphate (PIP

Indexed as

Cell LineGTP-Binding ProteinsHEK293 CellsHumansIon Channel GatingKCNQ Potassium ChannelsPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositolsGTP-Binding ProteinsKCNQ4 protein, humanKCNQ Potassium ChannelsPhosphatidylinositol 4,5-DiphosphatePhosphatidylinositolsG-protein βγIon channel regulationKCNQPIP2Potassium channel

Identifiers

PMID27981364
PMCPMC5222924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.