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ArticlePreventive medicine reports2017

Effectiveness of vaccination and wearing masks on seasonal influenza in Matsumoto City, Japan, in the 2014/2015 season: An observational study among all elementary schoolchildren.

Mitsuo Uchida, Minoru Kaneko, Yoshihiko Hidaka, Hiroshi Yamamoto, Takayuki Honda, Shouhei Takeuchi, Masaya Saito, Shigeyuki Kawa

Registry-linked trialAbstract read
In one paragraph

Article in Preventive medicine reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04337541 (Reduction in COVID-19 Infection Using Surgical Facial Masks Outside the Healthcare System), which is not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04337541 nacompletednot on this mapstarted 2020, after this paper: background citation

Reduction in COVID-19 Infection Using Surgical Facial Masks Outside the Healthcare System

TypeinterventionalSponsorRigshospitalet, DenmarkRan2020 to 2020Enrolled6,000ConditionsCOVID-19ArmsSurgical facial mask
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Children wearing face masks to prevent communicable diseases: scoping review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2022
    Article
  10. Article
  11. Within and between classroom transmission patterns of seasonal influenza among primary school students in Matsumoto city, Japan.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Community use of face masks and similar barriers to prevent respiratory illness such as COVID-19: a rapid scoping review.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2020
    Article
  17. Face coverings for the public: Laying straw men to rest.Journal of evaluation in clinical practice · 2020
    Article
  18. Why does Japan have so few cases of COVID-19?EMBO molecular medicine · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mitsuo UchidaCenter for Health, Safety and Environment Management, Shinshu University, Matsumoto, Nagano, Japan.
Minoru KanekoCenter for Health, Safety and Environment Management, Shinshu University, Matsumoto, Nagano, Japan.
Yoshihiko HidakaDepartment of Pediatrics, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Hiroshi YamamotoThe First Department of Internal Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Takayuki HondaDepartment of Laboratory Medicine, Shinshu University School of Medicine, Matsumoto, Nagano, Japan.
Shouhei TakeuchiDepartment of Public Health, Faculty of Medicine, University of Miyazaki, Miyazaki, Miyazaki, Japan.
Masaya SaitoInstitute of Statistical Mathematics, Tachikawa, Tokyo, Japan.
Shigeyuki KawaCenter for Health, Safety and Environment Management, Shinshu University, Matsumoto, Nagano, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measures of seasonal influenza control are generally divided into two categories: pharmaceutical and non-pharmaceutical interventions. The effectiveness of these measures remains unclear, because of insufficient study sample size and/or differences in study settings. This observational epidemiological study involved all elementary schoolchildren in Matsumoto City, Japan, with seasonal influenza during the 2014/2015 season. Questionnaires, including experiences with influenza diagnosis and socio-demographic factors, were distributed to all 29 public elementary schools, involving 13,217 children, at the end of February 2015. Data were obtained from 10,524 children and analyzed with multivariate logistic regression analysis. The result showed that vaccination (odds ratio 0.866, 95% confidence interval 0.786-0.954) and wearing masks (0.859, 0.778-0.949) had significant protective association. Hand washing (1.447, 1.274-1.644) and gargling (1.319, 1.183-1.471), however, were not associated with protection. In the natural setting, hand washing and gargling showed a negative association, which may have been due to inappropriate infection control measures or aggregating infected and non-infected children to conduct those measures. These results may indicate a pathway for influenza transmission and explain why seasonal influenza control remains difficult in school settings. The overall effectiveness of vaccination and mask wearing was 9.9% and 8.6%, respectively. After dividing children into higher (grades 4-6) and lower (grade 1-3) grade groups, the effectiveness of vaccination became greater in the lower grade group, and the effectiveness of wearing masks became greater in the higher grade group. These results may provide valuable information about designing infection control measures that allocate resources among children.

Indexed as

EffectivenessEfficacyEpidemiologyInfluenzaNPIsObservational studySchoolchildrenVaccine

Identifiers

PMID27981021
PMCPMC5153448

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.